Germline Variants

Explore data for individuals that are carriers of a TP53 germline variant and families in which at least one family member has been identified as a carrier of a germline variant in the TP53 gene.

Allows the retrieval and analysis of TP53 variants reported as germline events in human individuals. Each dataset entry corresponds to a tumor identified in an individual carrier of a TP53 germline variation.
Statistics are available on distribution of codon variants, TP53 variant distributions, tumor site distributions, and prevalence of TP53 germline variants in selected cohorts and dataset development.