TP53 Database: View Experimentally Induced Variants

Selected Rows 0

	Exposure	Genomic Description	cDNA Description	Protein Description	Model	Clone ID	Add Info	PubMed	MUT_ID:Induced_ID
5738	aristolochic acid	g.7673610T>A	c.920-2A>T	p.?	Hupki MEF	L9 HUF (R/R)	None	19030178	5738:30
1453	spontaneous immortalization	g.7675209del	c.403del	p.C135fs	Hupki MEF	HUF-CO-J-214	None	18765419	1453:113
1453	benz(a)anthracene-3,4-dione	g.7675209del	c.403del	p.C135fs	Yeast reporter gene assay	BAQ-69	None	22768918	1453:404
2108	AFB1 (aflatoxin)	g.7675092del	c.520del	p.R174fs	Human fibroblasts AG1521 (FASAY)	AFB1-16	Mutations identified on RNA by FASAY	18725321	2108:790
4044	AFB1 (aflatoxin)	g.7673743del	c.877del	p.G293fs	Human fibroblasts AG1521 (FASAY)	AFB1-41	Mutations identified on RNA by FASAY	18725321	4044:806
6723	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673820del	c.800del	p.R267fs	Hupki-XPAnull MEF	XN-BP-296	None	25847421	6723:902
4142	acetaldehyde	g.7673722del	c.898del	p.P300fs	Human fibroblasts AG1521 (FASAY)	Ac-39	Mutations identified on RNA by FASAY	18242117	4142:829
4002	B(a)P (benzo(a)Pyrene)	g.7673752del	c.868del	p.R290fs	Human fibroblasts AG1521 (FASAY)	BaP-37	Mutations identified on RNA by FASAY	22319594	4002:778
6205	benz(a)anthracene-3,4-dione	g.?	c.?(454del1)	p.?	Yeast reporter gene assay	BAQ-6	None	22768918	6205:412
6205	anti-B(a)PDE	g.?	c.?(454del1)	p.?	Yeast reporter gene assay	F-5	None	22768918	6205:515
2341	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674966del	c.565del	p.A189fs	Hupki-XPAnull MEF	XN-BP-206	None	25847421	2341:895
5616	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673540del	c.988del	p.L330fs	Hupki-XPAnull MEF	XN-BP-255	None	25847421	5616:910
2199	acetaldehyde	g.7675080del	c.532del	p.H178fs	Human fibroblasts AG1521 (FASAY)	Ac-13	Mutations identified on RNA by FASAY	18242117	2199:816
2199	benzene	g.7675080del	c.532del	p.H178fs	A549 human lung cell line	BIL15-BZ8	Mutations identified on RNA by FASAY	19862502	2199:946
6603	anti-B(a)PDE	g.7676102del	c.267del	p.P89fs	Yeast reporter gene assay	Am-53	methylated TP53 gene	22768918	6603:537
1866	benz(a)anthracene-3,4-dione	g.7675138del	c.474del	p.R158fs	Yeast reporter gene assay	BAQ-49	None	22768918	1866:413
1849	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675140del	c.472del	p.R158fs	Hupki MEF	XW-BP-73	None	25847421	1849:865
1738	dimethylbenz(a)anthracene-3,4-dione	g.7675157del	c.455del	p.P152fs	Yeast reporter gene assay	DB-17	None	22768918	1738:467
1738	dimethylbenz(a)anthracene-3,4-dione	g.7675157del	c.455del	p.P152fs	Yeast reporter gene assay	DB-27	None	22768918	1738:470
6793	benz(a)anthracene-3,4-dione	g.7673783del	c.837del	p.G279fs	Yeast reporter gene assay	BAQ-40	None	22768918	6793:449
4164	dimethylbenz(a)anthracene-3,4-dione	g.7673718del	c.902del	p.P301fs	Yeast reporter gene assay	DB-54	None	22768918	4164:505
4164	benzene	g.7673718del	c.902del	p.P301fs	A549 human lung cell line	BIL15-BZ22	Mutations identified on RNA by FASAY	19862502	4164:960
3896	benzene	g.7673772_7673773del	c.847_848del	p.R283fs	A549 human lung cell line	BIL15-BZ21	Mutations identified on RNA by FASAY	19862502	3896:959
6796	anti-B(a)PDE	g.7674193_7674197del	c.766_770del	p.T256fs	Yeast reporter gene assay	Am-14	methylated TP53 gene	22768918	6796:575
6802	B(a)P (benzo(a)Pyrene)	g.7674250_7674257del	c.706_713del	p.?	Human fibroblasts AG1521 (FASAY)	BaP-19	Mutations identified on RNA by FASAY	22319594	6802:765
6017	AFB1 (aflatoxin)	g.7674229_7674230insN	c.733_734insN	p.G245fs	Human fibroblasts AG1521 (FASAY)	AFB1-29	Mutations identified on RNA by FASAY	18725321	6017:798
6721	anti-B(a)PDE	g.7675208_7675209insN	c.403_404insN	p.C135fs	Yeast reporter gene assay	Am-24	methylated TP53 gene	22768918	6721:540
6801	B(a)P (benzo(a)Pyrene)	g.7675199_7675200insN	c.412_413insN	p.A138fs	Human fibroblasts AG1521 (FASAY)	BaP-8	Mutations identified on RNA by FASAY	22319594	6801:755
6681	acetaldehyde	g.7675189_7675190insN	c.422_423insN	p.C141fs	Human fibroblasts AG1521 (FASAY)	Ac-8	Mutations identified on RNA by FASAY	18242117	6681:811
2560	benz(a)anthracene-3,4-dione	g.7674921_7674922insNN	c.609_610insNN	p.E204fs	Yeast reporter gene assay	BAQ-58	None	22768918	2560:437
6792	benz(a)anthracene-3,4-dione	g.7674258_7674259insNN	c.704_705insNN	p.N235fs	Yeast reporter gene assay	BAQ-50	None	22768918	6792:444
3456	3-nitrobenzanthrone	g.7674196G>T	c.767C>A	p.T256K	Hupki MEF	HUF-3NBA-J-247	None	18765419	3456:98
1399	B(a)P-7,8-dione	g.7675219G>T	c.393C>A	p.N131K	Yeast reporter gene assay	OGG1-2A	OGG1 knock-out yeast	23117049	1399:639
3948	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673764C>T	c.856G>A	p.E286K	Yeast reporter gene assay	MNNG-10	None	12067251	3948:301
3948	anti-B(a)PDE	g.7673764C>T	c.856G>A	p.E286K	Yeast reporter gene assay	Am-12	methylated TP53 gene	22768918	3948:570
3948	acetaldehyde	g.7673764C>T	c.856G>A	p.E286K	Human fibroblasts AG1521 (FASAY)	Ac-34	Mutations identified on RNA by FASAY	18242117	3948:826
2201	B(a)P-7,8-dione	g.7675080G>T	c.532C>A	p.H178N	Yeast reporter gene assay	BPQ-A48	None	12067251	2201:261
2201	B(a)P radical cations	g.7675080G>T	c.532C>A	p.H178N	Yeast reporter gene assay	RC-25	None	22768918	2201:328
2201	acetaldehyde	g.7675080G>T	c.532C>A	p.H178N	Human fibroblasts AG1521 (FASAY)	Ac-12	Mutations identified on RNA by FASAY	18242117	2201:815
1792	B(a)P radical cations	g.7675148G>T	c.464C>A	p.T155N	Yeast reporter gene assay	RC-31	None	22768918	1792:334
1792	AFB1 (aflatoxin)	g.7675148G>T	c.464C>A	p.T155N	Human fibroblasts AG1521 (FASAY)	AFB1-13	Mutations identified on RNA by FASAY	18725321	1792:788
3856	spontaneous immortalization	g.7673779C>T	c.841G>A	p.D281N	Hupki MEF	HUF-CO-61	None	20118236	3856:179
3856	B(a)P-1,6 dione	g.7673779C>T	c.841G>A	p.D281N	Yeast reporter gene assay	1,6-81	None	22768918	3856:361
1534	spontaneous immortalization	g.7675195C>G	c.417G>C	p.K139N	Hupki MEF	HUF-CO-J-220	None	18765419	1534:116
1534	spontaneous immortalization	g.7675195C>G	c.417G>C	p.K139N	Hupki MEF	HUF-CO-17	None	20118236	1534:135
1938	B(a)P-3,6 dione	g.7675125A>T	c.487T>A	p.Y163N	Yeast reporter gene assay	3,6-2	None	22768918	1938:373
1603	dimethylbenz(a)anthracene-3,4-dione	g.7675182G>T	c.430C>A	p.Q144K	Yeast reporter gene assay	DB-58	None	22768918	1603:464
2229	B(a)P-7,8-dione	g.7675074C>T	c.538G>A	p.E180K	Yeast reporter gene assay	BPQ-BQ24	None	12067251	2229:263
2229	benz(a)anthracene-3,4-dione	g.7675074C>T	c.538G>A	p.E180K	Yeast reporter gene assay	BAQ-27	None	22768918	2229:424
2229	anti-B(a)PDE	g.7675074C>T	c.538G>A	p.E180K	Yeast reporter gene assay	Am-45	methylated TP53 gene	22768918	2229:554
3963	anti-B(a)PDE	g.7673761C>T	c.859G>A	p.E287K	Yeast reporter gene assay	Am-15	methylated TP53 gene	22768918	3963:571
3318	acetaldehyde	g.7674217C>T	c.746G>A	p.R249K	Human fibroblasts AG1521 (FASAY)	Ac-22	Mutations identified on RNA by FASAY	18242117	3318:820
3318	acetaldehyde	g.7674217C>T	c.746G>A	p.R249K	Human fibroblasts AG1521 (FASAY)	Ac-23	Mutations identified on RNA by FASAY	18242117	3318:853
3318	benzene	g.7674217C>T	c.746G>A	p.R249K	A549 human lung cell line	BIL15-BZ14	Mutations identified on RNA by FASAY	19862502	3318:952
3932	dimethylbenz(a)anthracene-3,4-dione	g.7673767C>T	c.853G>A	p.E285K	Yeast reporter gene assay	DB-32	None	22768918	3932:503
2868	B(a)P (benzo(a)Pyrene)	g.7674861C>T	c.670G>A	p.E224K	Human fibroblasts AG1521 (FASAY)	BaP-16	Mutations identified on RNA by FASAY	22319594	2868:763
3261	3-nitrobenzanthrone	g.7674226A>T	c.737T>A	p.M246K	Hupki MEF	HUF-3NBA-J-256	None	18765419	3261:96
3261	spontaneous immortalization	g.7674226A>T	c.737T>A	p.M246K	Hupki MEF	HUF-CO-42	None	20118236	3261:160
3085	benzene	g.7674253A>T	c.710T>A	p.M237K	A549 human lung cell line	BIL15-BZ11	Mutations identified on RNA by FASAY	19862502	3085:949
2218	B(a)P-7,8-dione	g.7675077G>T	c.535C>A	p.H179N	Yeast reporter gene assay	OGG1-40Z	OGG1 knock-out yeast	23117049	2218:672
2218	AFB1 (aflatoxin)	g.7675077G>T	c.535C>A	p.H179N	Human fibroblasts AG1521 (FASAY)	AFB1-18	Mutations identified on RNA by FASAY	18725321	2218:792
2218	AFB1 (aflatoxin)	g.7675077G>T	c.535C>A	p.H179N	Human fibroblasts AG1521 (FASAY)	AFB1-19	Mutations identified on RNA by FASAY	18725321	2218:839
2218	AFB1 (aflatoxin)	g.7675077G>T	c.535C>A	p.H179N	Human fibroblasts AG1521 (FASAY)	AFB1-20	Mutations identified on RNA by FASAY	18725321	2218:840
2218	3-nitrobenzanthrone	g.7675077G>T	c.535C>A	p.H179N	Hupki MEF	XW-3N-8	None	26723900	2218:922
1401	anti-B(a)PDE	g.7675219G>A	c.393C>T	p.N131N	Yeast reporter gene assay	AM7	None	18489080	1401:214
3286	UV radiation	g.7674222G>A	c.741C>T	p.N247N	Hupki skin	UV-5	None	11719445	3286:55
1535	B(a)P-3,6 dione	g.7675195C>A	c.417G>T	p.K139N	Yeast reporter gene assay	3,6-49	None	22768918	1535:388
4028	B(a)P-1,6 dione	g.7673747C>A	c.873G>T	p.K291N	Yeast reporter gene assay	1,6-57	None	22768918	4028:355
4028	B(a)P-1,6 dione	g.7673747C>A	c.873G>T	p.K291N	Yeast reporter gene assay	1,6-63	None	22768918	4028:358
4028	B(a)P-3,6 dione	g.7673747C>A	c.873G>T	p.K291N	Yeast reporter gene assay	3,6-79	None	22768918	4028:403
1964	anti-B(a)PDE	g.7675120C>A	c.492G>T	p.K164N	Yeast reporter gene assay	anti-BPDE-3	None	12067251	1964:229
2579	3-nitrobenzanthrone	g.7674918A>T	c.613T>A	p.Y205N	Hupki MEF	HUF-3NBA-J-260	None	18765419	2579:88
3850	spontaneous immortalization	g.7673781C>G	c.839G>C	p.R280T	Hupki MEF	HUF-CO-55	None	20118236	3850:173
3850	B(a)P radical cations	g.7673781C>G	c.839G>C	p.R280T	Yeast reporter gene assay	RC-8	None	22768918	3850:311
3850	B(a)P-7,8-dione	g.7673781C>G	c.839G>C	p.R280T	Yeast reporter gene assay	APN1-6	APN1 knock-out yeast	23117049	3850:708
3280	3-nitrobenzanthrone	g.7674223T>G	c.740A>C	p.N247T	Hupki MEF	HUF-3NBA-J-102	None	18765419	3280:97
3280	anti-B(a)PDE	g.7674223T>G	c.740A>C	p.N247T	Yeast reporter gene assay	anti-BPDE-2	None	12067251	3280:232
1395	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675220T>G	c.392A>C	p.N131T	Hupki-XPAnull MEF	XN-BP-300	None	25847421	1395:886
3459	B(a)P radical cations	g.7674195T>G	c.768A>C	p.T256T	Yeast reporter gene assay	RC-28	None	22768918	3459:331
3341	B(a)P-7,8-dione	g.7674215G>T	c.748C>A	p.P250T	Yeast reporter gene assay	APN1-7	APN1 knock-out yeast	23117049	3341:709
2804	B(a)P-3,6 dione	g.7674876G>T	c.655C>A	p.P219T	Yeast reporter gene assay	3,6-79	None	22768918	2804:402
2182	B(a)P radical cations	g.7675083G>T	c.529C>A	p.P177T	Yeast reporter gene assay	RC-16	None	22768918	2182:319
2182	B(a)P-7,8-dione	g.7675083G>T	c.529C>A	p.P177T	Yeast reporter gene assay	WT-36Z	Wild-type yeast	23117049	2182:617
2182	B(a)P-7,8-dione	g.7675083G>T	c.529C>A	p.P177T	Yeast reporter gene assay	OGG1-37Z	OGG1 knock-out yeast	23117049	2182:668
2182	B(a)P-7,8-dione	g.7675083G>T	c.529C>A	p.P177T	Yeast reporter gene assay	OGG1-75Z	OGG1 knock-out yeast	23117049	2182:699
3785	B(a)P-7,8-dione	g.7673794C>T	c.826G>A	p.A276T	Yeast reporter gene assay	OGG1-39Z	OGG1 knock-out yeast	23117049	3785:671
2446	spontaneous immortalization	g.7674947A>G	c.584T>C	p.I195T	Hupki MEF	HUF-CO-31	None	20118236	2446:149
3439	benz(a)anthracene-3,4-dione	g.7674199A>G	c.764T>C	p.I255T	Yeast reporter gene assay	BAQ-64	None	22768918	3439:445
3372	B(a)P radical cations	g.7674211A>G	c.752T>C	p.I251T	Yeast reporter gene assay	RC-10	None	22768918	3372:313
3372	B(a)P (benzo(a)Pyrene)	g.7674211A>G	c.752T>C	p.I251T	Human fibroblasts AG1521 (FASAY)	BaP-25	Mutations identified on RNA by FASAY	22319594	3372:769
1412	spontaneous immortalization	g.7675217T>G	c.395A>C	p.K132T	Hupki MEF	HUF-CO-5	None	20118236	1412:123
1247	spontaneous immortalization	g.7676010T>G	c.359A>C	p.K120T	Hupki MEF	HUF-CO-IV21	None	15805253	1247:78
1247	spontaneous immortalization	g.7676010T>G	c.359A>C	p.K120T	Hupki MEF	HUF-CO-4	None	20118236	1247:122
3319	3-nitrobenzanthrone	g.7674217C>G	c.746G>C	p.R249T	Hupki-XPAnull MEF	XN-3N-137	None	26723900	3319:933
3262	benz(a)anthracene-3,4-dione	g.7674226A>G	c.737T>C	p.M246T	Yeast reporter gene assay	BAQ18	None	18489080	3262:185
1572	B(a)P radical cations	g.7675188G>T	c.424C>A	p.P142T	Yeast reporter gene assay	RC-27	None	22768918	1572:330
1572	B(a)P-1,6 dione	g.7675188G>T	c.424C>A	p.P142T	Yeast reporter gene assay	1,6-23	None	22768918	1572:351
1572	anti-B(a)PDE	g.7675188G>T	c.424C>A	p.P142T	Yeast reporter gene assay	Am-59	methylated TP53 gene	22768918	1572:543
2853	benz(a)anthracene-3,4-dione	g.7674864G>T	c.667C>A	p.P223T	Yeast reporter gene assay	BAQ-60	None	22768918	2853:430
3414	dimethylbenz(a)anthracene-3,4-dione	g.7674204G>A	c.759C>T	p.T253T	Yeast reporter gene assay	DB-21	None	22768918	3414:475
4224	B(a)P-7,8-dione	g.7673704G>T	c.916C>A	p.R306R	Yeast reporter gene assay	OGG1-35Z	OGG1 knock-out yeast	23117049	4224:666
3153	B(a)P-7,8-dione	g.7674243A>T	c.720T>A	p.S240R	Yeast reporter gene assay	APN1-23A	APN1 knock-out yeast	23117049	3153:723
3133	spontaneous immortalization	g.7674247T>C	c.716A>G	p.N239S	Hupki MEF	HUF-CO-33	None	20118236	3133:151
1856	benz(a)anthracene-3,4-dione	g.7675140G>T	c.472C>A	p.R158S	Yeast reporter gene assay	BAQ-25	None	22768918	1856:414
3899	anti-B(a)PDE	g.7673773G>T	c.847C>A	p.R283S	Yeast reporter gene assay	anti-BPDE-21	None	12067251	3899:235
3899	B(a)P-7,8-dione	g.7673773G>T	c.847C>A	p.R283S	Yeast reporter gene assay	BPQ-A53	None	12067251	3899:294
3899	benz(a)anthracene-3,4-dione	g.7673773G>T	c.847C>A	p.R283S	Yeast reporter gene assay	BAQ-2	None	22768918	3899:453
3899	B(a)P-7,8-dione	g.7673773G>T	c.847C>A	p.R283S	Yeast reporter gene assay	WT-23Z	Wild-type yeast	23117049	3899:610
3899	B(a)P-7,8-dione	g.7673773G>T	c.847C>A	p.R283S	Yeast reporter gene assay	WT-61Z	Wild-type yeast	23117049	3899:626
2240	anti-B(a)PDE	g.7675071G>T	c.541C>A	p.R181S	Yeast reporter gene assay	Am-52	methylated TP53 gene	22768918	2240:555
2240	B(a)P (benzo(a)Pyrene)	g.7675071G>T	c.541C>A	p.R181S	Human fibroblasts AG1521 (FASAY)	BaP-15	Mutations identified on RNA by FASAY	22319594	2240:762
3236	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674230C>T	c.733G>A	p.G245S	Yeast reporter gene assay	MNNG-10	None	12067251	3236:300
3236	AFB1 (aflatoxin)	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	AFB1-31	Mutations identified on RNA by FASAY	18725321	3236:800
3236	AFB1 (aflatoxin)	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	AFB1-32	Mutations identified on RNA by FASAY	18725321	3236:844
3236	AFB1 (aflatoxin)	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	AFB1-33	Mutations identified on RNA by FASAY	18725321	3236:845
3236	AFB1 (aflatoxin)	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	AFB1-34	Mutations identified on RNA by FASAY	18725321	3236:846
3236	AFB1 (aflatoxin)	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	AFB1-35	Mutations identified on RNA by FASAY	18725321	3236:847
3236	acetaldehyde	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	Ac-14	Mutations identified on RNA by FASAY	18242117	3236:817
3236	acetaldehyde	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	Ac-15	Mutations identified on RNA by FASAY	18242117	3236:848
3236	acetaldehyde	g.7674230C>T	c.733G>A	p.G245S	Human fibroblasts AG1521 (FASAY)	Ac-16	Mutations identified on RNA by FASAY	18242117	3236:849
1768	B(a)P-1,6 dione	g.7675152C>T	c.460G>A	p.G154S	Yeast reporter gene assay	1,6-18	None	22768918	1768:347
2897	benz(a)anthracene-3,4-dione	g.7674287C>T	c.676G>A	p.G226S	Yeast reporter gene assay	BAQ-16	None	22768918	2897:406
2897	benz(a)anthracene-3,4-dione	g.7674287C>T	c.676G>A	p.G226S	Yeast reporter gene assay	BAQ-44	None	22768918	2897:443
2897	dimethylbenz(a)anthracene-3,4-dione	g.7674287C>T	c.676G>A	p.G226S	Yeast reporter gene assay	DB-20	None	22768918	2897:462
2897	B(a)P-7,8-dione	g.7674287C>T	c.676G>A	p.G226S	Yeast reporter gene assay	WT-24BP	Wild-type yeast	23117049	2897:606
3326	spontaneous immortalization	g.7674216C>G	c.747G>C	p.R249S	Hupki MEF	HUF-CO-IV13	None	15805253	3326:77
3326	spontaneous immortalization	g.7674216C>G	c.747G>C	p.R249S	Hupki MEF	HUF-CO-43	None	20118236	3326:161
3326	spontaneous immortalization	g.7674216C>G	c.747G>C	p.R249S	Hupki MEF	HUF-CO-44	None	20118236	3326:162
3326	B(a)P-7,8-dione	g.7674216C>G	c.747G>C	p.R249S	Yeast reporter gene assay	BPQ-BQ17	None	12067251	3326:284
3326	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674216C>G	c.747G>C	p.R249S	Hupki MEF	XW-BP-2	None	25847421	3326:876
3326	3-nitrobenzanthrone	g.7674216C>G	c.747G>C	p.R249S	Hupki MEF	XW-3N-14	None	26723900	3326:927
3440	spontaneous immortalization	g.7674199A>C	c.764T>G	p.I255S	Hupki MEF	HUF-CO-45	None	20118236	3440:163
3440	spontaneous immortalization	g.7674199A>C	c.764T>G	p.I255S	Hupki MEF	HUF-CO-46	None	20118236	3440:164
2994	B(a)P radical cations	g.7674268A>C	c.695T>G	p.I232S	Yeast reporter gene assay	RC-7	None	22768918	2994:310
2994	B(a)P radical cations	g.7674268A>C	c.695T>G	p.I232S	Yeast reporter gene assay	RC-12	None	22768918	2994:315
1413	B(a)P-7,8-dione	g.7675217T>C	c.395A>G	p.K132R	Yeast reporter gene assay	BPQ-A22	None	12067251	1413:236
3877	B(a)P-7,8-dione	g.7673776G>T	c.844C>A	p.R282R	Yeast reporter gene assay	OGG1-56Z	OGG1 knock-out yeast	23117049	3877:682
5077	B(a)P-7,8-dione	g.7669626C>T	c.1165G>A	p.G389R	Yeast reporter gene assay	WT-19	Wild-type yeast	23117049	5077:595
3155	3-nitrobenzanthrone	g.7674243A>C	c.720T>G	p.S240R	Hupki MEF	HUF-CO-J-224	None	18765419	3155:104
3155	spontaneous immortalization	g.7674243A>C	c.720T>G	p.S240R	Hupki MEF	HUF-CO-34	None	20118236	3155:152
1893	B(a)P-7,8-dione	g.7675133A>C	c.479T>G	p.M160R	Yeast reporter gene assay	APN1-4	APN1 knock-out yeast	23117049	1893:707
3087	benzene	g.7674253A>C	c.710T>G	p.M237R	A549 human lung cell line	BIL15-BZ12	Mutations identified on RNA by FASAY	19862502	3087:950
3263	B(a)P-7,8-dione	g.7674226A>C	c.737T>G	p.M246R	Yeast reporter gene assay	WT-20P	Wild-type yeast	23117049	3263:602
3854	aristolochic acid	g.7673780T>A	c.840A>T	p.R280S	Hupki MEF	L8 HUF (R/R)	None	19030178	3854:28
3854	benz(a)anthracene-3,4-dione	g.7673780T>A	c.840A>T	p.R280S	Yeast reporter gene assay	BAQ-21	None	22768918	3854:428
3728	benz(a)anthracene-3,4-dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	BAQ59	None	18489080	3728:188
3728	benz(a)anthracene-3,4-dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	BAQ1	None	18489080	3728:189
3728	dimethylbenz(a)anthracene-3,4-dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	DB2	None	18489080	3728:193
3728	B(a)P-3,6 dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	3,6-76	None	22768918	3728:401
3728	benz(a)anthracene-3,4-dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	BAQ-26	None	22768918	3728:423
3728	B(a)P-7,8-dione	g.7673803G>T	c.817C>A	p.R273S	Yeast reporter gene assay	OGG1-71Z	OGG1 knock-out yeast	23117049	3728:695
3728	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673803G>T	c.817C>A	p.R273S	Hupki-XPAnull MEF	XN-BP-251	None	25847421	3728:906
3728	3-nitrobenzanthrone	g.7673803G>T	c.817C>A	p.R273S	Hupki-XPAnull MEF	XN-3N-156	None	26723900	3728:934
3553	anti-B(a)PDE	g.7673836C>T	c.784G>A	p.G262S	Yeast reporter gene assay	P-4	None	22768918	3553:526
3766	anti-B(a)PDE	g.7673797A>T	c.823T>A	p.C275S	Yeast reporter gene assay	Am-9	methylated TP53 gene	22768918	3766:567
2450	B(a)P-7,8-dione	g.7674946G>T	c.585C>A	p.I195I	Yeast reporter gene assay	OGG1-78ZA	OGG1 knock-out yeast	23117049	2450:701
1930	B(a)P-7,8-dione	g.7675126G>T	c.486C>A	p.I162I	Yeast reporter gene assay	BPQ-A43	None	12067251	1930:292
1930	B(a)P-7,8-dione	g.7675126G>T	c.486C>A	p.I162I	Yeast reporter gene assay	OGG1-29B	OGG1 knock-out yeast	23117049	1930:657
2039	benz(a)anthracene-3,4-dione	g.7675105C>T	c.507G>A	p.M169I	Yeast reporter gene assay	BAQ-23	None	22768918	2039:417
3090	anti-B(a)PDE	g.7674252C>T	c.711G>A	p.M237I	Yeast reporter gene assay	F-16	None	22768918	3090:521
3206	anti-B(a)PDE	g.7674234C>T	c.729G>A	p.M243I	Yeast reporter gene assay	F-2	None	22768918	3206:523
3265	B(a)P-7,8-dione	g.7674225C>T	c.738G>A	p.M246I	Yeast reporter gene assay	BPQ-I12	None	12067251	3265:282
3265	B(a)P-3,6 dione	g.7674225C>T	c.738G>A	p.M246I	Yeast reporter gene assay	3,6-6	None	22768918	3265:374
3851	3-nitrobenzanthrone	g.7673781C>A	c.839G>T	p.R280I	Hupki MEF	HUF-3NBA-J-265	None	18765419	3851:103
3851	B(a)P radical cations	g.7673781C>A	c.839G>T	p.R280I	Yeast reporter gene assay	RC-24	None	22768918	3851:327
3851	B(a)P-7,8-dione	g.7673781C>A	c.839G>T	p.R280I	Yeast reporter gene assay	OGG1-25	OGG1 knock-out yeast	23117049	3851:653
1397	aristolochic acid	g.7675220T>A	c.392A>T	p.N131I	Hupki MEF	L112 HUF (R/P)	None	19030178	1397:9
1794	B(a)P-7,8-dione	g.7675148G>A	c.464C>T	p.T155I	Yeast reporter gene assay	BPQ-BQ9	None	12067251	1794:251
1794	B(a)P-7,8-dione	g.7675148G>A	c.464C>T	p.T155I	Yeast reporter gene assay	WT-23P	Wild-type yeast	23117049	1794:604
1794	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675148G>A	c.464C>T	p.T155I	Hupki-XPAnull MEF	XN-BP-204	None	25847421	1794:888
1547	dimethylbenz(a)anthracene-3,4-dione	g.7675193G>A	c.419C>T	p.T140I	Yeast reporter gene assay	DB-52	None	22768918	1547:458
3409	benz(a)anthracene-3,4-dione	g.7674205G>A	c.758C>T	p.T253I	Yeast reporter gene assay	BAQ-55	None	22768918	3409:441
1835	B(a)P-7,8-dione	g.7675143C>T	c.469G>A	p.V157I	Yeast reporter gene assay	BPQ-A11	None	12067251	1835:252
3091	dimethylbenz(a)anthracene-3,4-dione	g.7674252C>G	c.711G>C	p.M237I	Yeast reporter gene assay	DB-38	None	22768918	3091:488
3207	anti-B(a)PDE	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	anti-BPDE-15	None	12067251	3207:231
3207	B(a)P-7,8-dione	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	BPQ-BQ14	None	12067251	3207:277
3207	B(a)P radical cations	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	RC-21	None	22768918	3207:324
3207	anti-B(a)PDE	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	P-5	None	22768918	3207:522
3207	anti-B(a)PDE	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	F-27	None	22768918	3207:524
3207	anti-B(a)PDE	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	Am-4	methylated TP53 gene	22768918	3207:547
3207	anti-B(a)PDE	g.7674234C>G	c.729G>C	p.M243I	Yeast reporter gene assay	Am-55	methylated TP53 gene	22768918	3207:557
4192	B(a)P-3,6 dione	g.7673712C>A	c.908G>T	p.S303I	Yeast reporter gene assay	3,6-17	None	22768918	4192:380
1414	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675217T>A	c.395A>T	p.K132M	Human fibroblasts AG1521 (FASAY)	XW-BP-10	None	25847421	1414:862
1249	3-nitrobenzanthrone	g.7676010T>A	c.359A>T	p.K120M	Hupki MEF	XW-3N-9	None	26723900	1249:915
4217	anti-B(a)PDE	g.7673706T>A	c.914A>T	p.K305M	Yeast reporter gene assay	F-3	None	22768918	4217:528
4217	AFB1 (aflatoxin)	g.7673706T>A	c.914A>T	p.K305M	Human fibroblasts AG1521 (FASAY)	AFB1-44	Mutations identified on RNA by FASAY	18725321	4217:809
3600	benz(a)anthracene-3,4-dione	g.7673827G>T	c.793C>A	p.L265M	Yeast reporter gene assay	BAQ-16	None	22768918	3600:407
1139	B(a)P-7,8-dione	g.7676038G>T	c.331C>A	p.L111M	Yeast reporter gene assay	APN1-11	APN1 knock-out yeast	23117049	1139:712
2451	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674946G>C	c.585C>G	p.I195M	Hupki MEF	XW-BP-17	None	25847421	2451:867
2050	B(a)P-7,8-dione	g.7675103G>A	c.509C>T	p.T170M	Yeast reporter gene assay	WT-45Z	Wild-type yeast	23117049	2050:623
2050	B(a)P-7,8-dione	g.7675103G>A	c.509C>T	p.T170M	Yeast reporter gene assay	WT-47Z	Wild-type yeast	23117049	2050:624
2050	B(a)P-7,8-dione	g.7675103G>A	c.509C>T	p.T170M	Yeast reporter gene assay	APN1-25A	APN1 knock-out yeast	23117049	2050:726
2050	B(a)P-7,8-dione	g.7675103G>A	c.509C>T	p.T170M	Yeast reporter gene assay	APN1-30A	APN1 knock-out yeast	23117049	2050:731
1586	spontaneous immortalization	g.7675185C>T	c.427G>A	p.V143M	Hupki MEF	HUF-CO-18	None	20118236	1586:136
1586	dimethylbenz(a)anthracene-3,4-dione	g.7675185C>T	c.427G>A	p.V143M	Yeast reporter gene assay	DB-20	None	22768918	1586:461
1586	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675185C>T	c.427G>A	p.V143M	Human fibroblasts AG1521 (FASAY)	XW-BP-50	None	25847421	1586:863
2754	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674885C>T	c.646G>A	p.V216M	Yeast reporter gene assay	MNNG-9	None	12067251	2754:222
2754	dimethylbenz(a)anthracene-3,4-dione	g.7674885C>T	c.646G>A	p.V216M	Yeast reporter gene assay	DB-23	None	22768918	2754:485
2754	AFB1 (aflatoxin)	g.7674885C>T	c.646G>A	p.V216M	Human fibroblasts AG1521 (FASAY)	AFB1-22	Mutations identified on RNA by FASAY	18725321	2754:794
2772	benz(a)anthracene-3,4-dione	g.7674882C>T	c.649G>A	p.V217M	Yeast reporter gene assay	BAQ-55	None	22768918	2772:440
2094	spontaneous immortalization	g.7675095C>T	c.517G>A	p.V173M	Hupki MEF	HUF-CO-23	None	20118236	2094:141
2094	dimethylbenz(a)anthracene-3,4-dione	g.7675095C>T	c.517G>A	p.V173M	Yeast reporter gene assay	DB-21	None	22768918	2094:474
2094	dimethylbenz(a)anthracene-3,4-dione	g.7675095C>T	c.517G>A	p.V173M	Yeast reporter gene assay	DB-61	None	22768918	2094:476
3711	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673806C>T	c.814G>A	p.V272M	Hupki MEF	MNNG 77 HUF (R/P)	None	19030178	3711:39
3711	B(a)P-7,8-dione	g.7673806C>T	c.814G>A	p.V272M	Yeast reporter gene assay	OGG1-33ZA	OGG1 knock-out yeast	23117049	3711:664
3711	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673806C>T	c.814G>A	p.V272M	Hupki-XPAnull MEF	XN-BP-210	None	25847421	3711:903
3320	B(a)P-7,8-dione	g.7674217C>A	c.746G>T	p.R249M	Yeast reporter gene assay	BPQ-BQ8	None	12067251	3320:283
3980	AFB1 (aflatoxin)	g.7673757T>A	c.863A>T	p.N288I	Human fibroblasts AG1521 (FASAY)	AFB1-40	Mutations identified on RNA by FASAY	18725321	3980:805
3980	acetaldehyde	g.7673757T>A	c.863A>T	p.N288I	Human fibroblasts AG1521 (FASAY)	Ac-35	Mutations identified on RNA by FASAY	18242117	3980:827
3980	acetaldehyde	g.7673757T>A	c.863A>T	p.N288I	Human fibroblasts AG1521 (FASAY)	Ac-36	Mutations identified on RNA by FASAY	18242117	3980:859
2423	B(a)P-7,8-dione	g.7674951G>T	c.580C>A	p.L194I	Yeast reporter gene assay	OGG1-68Z	OGG1 knock-out yeast	23117049	2423:693
4506	B(a)P-7,8-dione	g.7673540G>T	c.988C>A	p.L330I	Yeast reporter gene assay	BPQ-B90	None	12067251	4506:240
2997	dimethylbenz(a)anthracene-3,4-dione	g.7674267G>A	c.696C>T	p.I232I	Yeast reporter gene assay	DB-38	None	22768918	2997:487
2452	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674946G>A	c.585C>T	p.I195I	Yeast reporter gene assay	MNNG-11	None	12067251	2452:302
3208	dimethylbenz(a)anthracene-3,4-dione	g.7674234C>A	c.729G>T	p.M243I	Yeast reporter gene assay	DB-19	None	22768918	3208:495
3208	dimethylbenz(a)anthracene-3,4-dione	g.7674234C>A	c.729G>T	p.M243I	Yeast reporter gene assay	DB-29	None	22768918	3208:496
3208	anti-B(a)PDE	g.7674234C>A	c.729G>T	p.M243I	Yeast reporter gene assay	Am-10	methylated TP53 gene	22768918	3208:565
3208	B(a)P-7,8-dione	g.7674234C>A	c.729G>T	p.M243I	Yeast reporter gene assay	APN1-31	APN1 knock-out yeast	23117049	3208:733
3267	benz(a)anthracene-3,4-dione	g.7674225C>A	c.738G>T	p.M246I	Yeast reporter gene assay	BAQ32	None	18489080	3267:184
2210	3-nitrobenzanthrone	g.7675078G>T	c.534C>A	p.H178Q	Hupki MEF	XW-3N-54	None	26723900	2210:921
4099	B(a)P-1,6 dione	g.7673732G>T	c.888C>A	p.H296Q	Yeast reporter gene assay	1,6-91	None	22768918	4099:371
4227	dimethylbenz(a)anthracene-3,4-dione	g.7673703C>T	c.917G>A	p.R306Q	Yeast reporter gene assay	DB-57	None	22768918	4227:494
4227	anti-B(a)PDE	g.7673703C>T	c.917G>A	p.R306Q	Yeast reporter gene assay	Am-35	methylated TP53 gene	22768918	4227:572
2008	anti-B(a)PDE	g.7675111C>T	c.501G>A	p.Q167Q	Yeast reporter gene assay	Am-39	methylated TP53 gene	22768918	2008:553
2706	anti-B(a)PDE	g.7674893C>T	c.638G>A	p.R213Q	Yeast reporter gene assay	Am-32	methylated TP53 gene	22768918	2706:559
3300	UV radiation	g.7674219_7674220delinsTT	c.743_744delinsAA	p.R248Q	Hupki skin	UV-3	None	11719445	3300:53
4266	B(a)P radical cations	g.7673602G>T	c.926C>A	p.P309H	Yeast reporter gene assay	RC-23	None	22768918	4266:326
2808	B(a)P-7,8-dione	g.7674875G>T	c.656C>A	p.P219H	Yeast reporter gene assay	WT-24AP	Wild-type yeast	23117049	2808:605
1721	B(a)P-7,8-dione	g.7675160G>T	c.452C>A	p.P151H	Yeast reporter gene assay	WT-39Z	Wild-type yeast	23117049	1721:619
1756	B(a)P-1,6 dione	g.7675154G>T	c.458C>A	p.P153H	Yeast reporter gene assay	1,6-18	None	22768918	1756:346
2188	B(a)P radical cations	g.7675082G>T	c.530C>A	p.P177H	Yeast reporter gene assay	RC-30	None	22768918	2188:333
2188	B(a)P-7,8-dione	g.7675082G>T	c.530C>A	p.P177H	Yeast reporter gene assay	OGG1-79Z	OGG1 knock-out yeast	23117049	2188:703
2188	B(a)P (benzo(a)Pyrene)	g.7675082G>T	c.530C>A	p.P177H	Human fibroblasts AG1521 (FASAY)	BaP-13	Mutations identified on RNA by FASAY	22319594	2188:760
1861	B(a)P-3,6 dione	g.7675139C>T	c.473G>A	p.R158H	Yeast reporter gene assay	3,6-35	None	22768918	1861:384
1861	B(a)P-7,8-dione	g.7675139C>T	c.473G>A	p.R158H	Yeast reporter gene assay	WT-39P	Wild-type yeast	23117049	1861:609
1861	benzene	g.7675139C>T	c.473G>A	p.R158H	A549 human lung cell line	BIL15-BZ7	Mutations identified on RNA by FASAY	19862502	1861:945
3903	B(a)P-1,6 dione	g.7673772C>T	c.848G>A	p.R283H	Yeast reporter gene assay	1,6-29	None	22768918	3903:352
3903	dimethylbenz(a)anthracene-3,4-dione	g.7673772C>T	c.848G>A	p.R283H	Yeast reporter gene assay	DB-4	None	22768918	3903:501
3903	dimethylbenz(a)anthracene-3,4-dione	g.7673772C>T	c.848G>A	p.R283H	Yeast reporter gene assay	DB-53	None	22768918	3903:502
3903	B(a)P-7,8-dione	g.7673772C>T	c.848G>A	p.R283H	Yeast reporter gene assay	OGG1-5	OGG1 knock-out yeast	23117049	3903:643
3903	B(a)P (benzo(a)Pyrene)	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	BaP-33	Mutations identified on RNA by FASAY	22319594	3903:775
3903	B(a)P (benzo(a)Pyrene)	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	BaP-34	Mutations identified on RNA by FASAY	22319594	3903:837
3903	AFB1 (aflatoxin)	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	AFB1-39	Mutations identified on RNA by FASAY	18725321	3903:804
3903	acetaldehyde	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	Ac-31	Mutations identified on RNA by FASAY	18242117	3903:825
3903	acetaldehyde	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	Ac-32	Mutations identified on RNA by FASAY	18242117	3903:857
3903	acetaldehyde	g.7673772C>T	c.848G>A	p.R283H	Human fibroblasts AG1521 (FASAY)	Ac-33	Mutations identified on RNA by FASAY	18242117	3903:858
2245	B(a)P-3,6 dione	g.7675070C>T	c.542G>A	p.R181H	Yeast reporter gene assay	3,6-19	None	22768918	2245:381
2245	B(a)P-3,6 dione	g.7675070C>T	c.542G>A	p.R181H	Yeast reporter gene assay	3,6-69	None	22768918	2245:395
2245	B(a)P-3,6 dione	g.7675070C>T	c.542G>A	p.R181H	Yeast reporter gene assay	3,6-73	None	22768918	2245:398
2245	B(a)P-3,6 dione	g.7675070C>T	c.542G>A	p.R181H	Yeast reporter gene assay	3,6-74	None	22768918	2245:400
2245	dimethylbenz(a)anthracene-3,4-dione	g.7675070C>T	c.542G>A	p.R181H	Yeast reporter gene assay	DB-10	None	22768918	2245:478
2143	spontaneous immortalization	g.7675088C>T	c.524G>A	p.R175H	Hupki MEF	HUF-CO-24	None	20118236	2143:142
2143	B(a)P-1,6 dione	g.7675088C>T	c.524G>A	p.R175H	Yeast reporter gene assay	1,6-83	None	22768918	2143:364
2143	B(a)P-7,8-dione	g.7675088C>T	c.524G>A	p.R175H	Yeast reporter gene assay	APN1-17	APN1 knock-out yeast	23117049	2143:717
2143	B(a)P (benzo(a)Pyrene)	g.7675088C>T	c.524G>A	p.R175H	Human fibroblasts AG1521 (FASAY)	BaP-12	Mutations identified on RNA by FASAY	22319594	2143:759
2143	AFB1 (aflatoxin)	g.7675088C>T	c.524G>A	p.R175H	Human fibroblasts AG1521 (FASAY)	AFB1-17	Mutations identified on RNA by FASAY	18725321	2143:791
2401	anti-B(a)PDE	g.7674955C>G	c.576G>C	p.Q192H	Yeast reporter gene assay	F26	None	18489080	2401:213
3857	spontaneous immortalization	g.7673779C>G	c.841G>C	p.D281H	Hupki MEF	HUF-CO-56	None	20118236	3857:174
3857	spontaneous immortalization	g.7673779C>G	c.841G>C	p.D281H	Hupki MEF	HUF-CO-57	None	20118236	3857:175
3857	dimethylbenz(a)anthracene-3,4-dione	g.7673779C>G	c.841G>C	p.D281H	Yeast reporter gene assay	DB62	None	18489080	3857:196
1382	aristolochic acid	g.7675223A>T	c.389T>A	p.L130H	Hupki MEF	L13 HUF (R/R)	None	19030178	1382:34
1939	B(a)P-7,8-dione	g.7675125A>G	c.487T>C	p.Y163H	Yeast reporter gene assay	BPQ-A40	None	12067251	1939:254
3021	B(a)P (benzo(a)Pyrene)	g.7674263A>G	c.700T>C	p.Y234H	Human fibroblasts AG1521 (FASAY)	BaP-17	Mutations identified on RNA by FASAY	22319594	3021:764
3021	B(a)P (benzo(a)Pyrene)	g.7674263A>G	c.700T>C	p.Y234H	Human fibroblasts AG1521 (FASAY)	BaP-18	Mutations identified on RNA by FASAY	22319594	3021:834
1321	B(a)P-1,6 dione	g.7675236A>G	c.376T>C	p.Y126H	Yeast reporter gene assay	1,6-60	None	22768918	1321:356
3059	B(a)P-7,8-dione	g.7674257A>G	c.706T>C	p.Y236H	Yeast reporter gene assay	WT-2P	Wild-type yeast	23117049	3059:598
1739	benz(a)anthracene-3,4-dione	g.7675157G>T	c.455C>A	p.P152Q	Yeast reporter gene assay	BAQ-38	None	22768918	1739:411
1739	dimethylbenz(a)anthracene-3,4-dione	g.7675157G>T	c.455C>A	p.P152Q	Yeast reporter gene assay	DB-25	None	22768918	1739:468
2026	aristolochic acid	g.7675108G>C	c.504C>G	p.H168Q	Hupki MEF	L113 HUF (R/P)	None	19030178	2026:10
2211	B(a)P-7,8-dione	g.7675078G>C	c.534C>G	p.H178Q	Yeast reporter gene assay	APN1-18B	APN1 knock-out yeast	23117049	2211:719
3297	UV radiation	g.7674220C>T	c.743G>A	p.R248Q	Hupki skin	UV-1	None	11719445	3297:51
3297	B(a)P-1,6 dione	g.7674220C>T	c.743G>A	p.R248Q	Yeast reporter gene assay	1,6-94	None	22768918	3297:372
3297	B(a)P (benzo(a)Pyrene)	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	BaP-22	Mutations identified on RNA by FASAY	22319594	3297:768
3297	B(a)P (benzo(a)Pyrene)	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	BaP-23	Mutations identified on RNA by FASAY	22319594	3297:835
3297	B(a)P (benzo(a)Pyrene)	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	BaP-24	Mutations identified on RNA by FASAY	22319594	3297:836
3297	acetaldehyde	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	Ac-18	Mutations identified on RNA by FASAY	18242117	3297:819
3297	acetaldehyde	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	Ac-19	Mutations identified on RNA by FASAY	18242117	3297:850
3297	acetaldehyde	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	Ac-20	Mutations identified on RNA by FASAY	18242117	3297:851
3297	acetaldehyde	g.7674220C>T	c.743G>A	p.R248Q	Human fibroblasts AG1521 (FASAY)	Ac-21	Mutations identified on RNA by FASAY	18242117	3297:852
3297	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674220C>T	c.743G>A	p.R248Q	Hupki MEF	XW-BP-16	None	25847421	3297:873
3297	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674220C>T	c.743G>A	p.R248Q	Hupki MEF	XW-BP-55	None	25847421	3297:874
3883	AFB1 (aflatoxin)	g.7673775C>T	c.845G>A	p.R282Q	Human fibroblasts AG1521 (FASAY)	AFB1-38	Mutations identified on RNA by FASAY	18725321	3883:803
3634	B(a)P-1,6 dione	g.7673820C>T	c.800G>A	p.R267Q	Yeast reporter gene assay	1,6-65	None	22768918	3634:359
3634	B(a)P-3,6 dione	g.7673820C>T	c.800G>A	p.R267Q	Yeast reporter gene assay	3,6-15	None	22768918	3634:378
2567	B(a)P-7,8-dione	g.7674921C>G	c.610G>C	p.E204Q	Yeast reporter gene assay	BPQ-A15	None	12067251	2567:270
2230	B(a)P radical cations	g.7675074C>G	c.538G>C	p.E180Q	Yeast reporter gene assay	RC-3	None	22768918	2230:306
2230	anti-B(a)PDE	g.7675074C>G	c.538G>C	p.E180Q	Yeast reporter gene assay	F-20	None	22768918	2230:518
3603	B(a)P radical cations	g.7673826A>T	c.794T>A	p.L265Q	Yeast reporter gene assay	RC-9	None	22768918	3603:312
3603	AFB1 (aflatoxin)	g.7673826A>T	c.794T>A	p.L265Q	Human fibroblasts AG1521 (FASAY)	AFB1-37	Mutations identified on RNA by FASAY	18725321	3603:802
3470	anti-B(a)PDE	g.7674193A>T	c.770T>A	p.L257Q	Yeast reporter gene assay	AM7	None	18489080	3470:215
3470	B(a)P-1,6 dione	g.7674193A>T	c.770T>A	p.L257Q	Yeast reporter gene assay	1,6-85	None	22768918	3470:365
1354	3-nitrobenzanthrone	g.7675229G>T	c.383C>A	p.P128H	Hupki MEF	HUF-3NBA-J-256	None	18765419	1354:79
3815	UV radiation	g.7673787G>T	c.833C>A	p.P278H	Hupki skin	UV-10	None	11719445	3815:60
3815	dimethylbenz(a)anthracene-3,4-dione	g.7673787G>T	c.833C>A	p.P278H	Yeast reporter gene assay	DB24	None	18489080	3815:209
3815	B(a)P-7,8-dione	g.7673787G>T	c.833C>A	p.P278H	Yeast reporter gene assay	BPQ-A43	None	12067251	3815:290
3815	benz(a)anthracene-3,4-dione	g.7673787G>T	c.833C>A	p.P278H	Yeast reporter gene assay	BAQ-	None	22768918	3815:409
4082	AFB1 (aflatoxin)	g.7673736G>T	c.884C>A	p.P295H	Human fibroblasts AG1521 (FASAY)	AFB1-42	Mutations identified on RNA by FASAY	18725321	4082:807
2382	B(a)P-7,8-dione	g.7674959G>T	c.572C>A	p.P191H	Yeast reporter gene assay	WT-42Z	Wild-type yeast	23117049	2382:621
2212	B(a)P-7,8-dione	g.7675078G>A	c.534C>T	p.H178H	Yeast reporter gene assay	WT-6	Wild-type yeast	23117049	2212:587
2027	B(a)P-1,6 dione	g.7675108G>A	c.504C>T	p.H168H	Yeast reporter gene assay	1,6-83	None	22768918	2027:363
3737	B(a)P (benzo(a)Pyrene)	g.7673802C>T	c.818G>A	p.R273H	Hupki MEF	HUF-BaP-13	None	15805253	3737:64
3737	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673802C>T	c.818G>A	p.R273H	Yeast reporter gene assay	MNNG-1	None	12067251	3737:299
1659	B(a)P-3,6 dione	g.7675170C>G	c.442G>C	p.D148H	Yeast reporter gene assay	3,6-72	None	22768918	1659:396
1060	B(a)P (benzo(a)Pyrene)	g.7676057C>A	c.312G>T	p.Q104H	Human fibroblasts AG1521 (FASAY)	BaP-1	Mutations identified on RNA by FASAY	22319594	1060:748
2818	AFB1 (aflatoxin)	g.7674873A>G	c.658T>C	p.Y220H	Human fibroblasts AG1521 (FASAY)	AFB1-23	Mutations identified on RNA by FASAY	18725321	2818:795
2818	AFB1 (aflatoxin)	g.7674873A>G	c.658T>C	p.Y220H	Human fibroblasts AG1521 (FASAY)	AFB1-24	Mutations identified on RNA by FASAY	18725321	2818:841
2818	AFB1 (aflatoxin)	g.7674873A>G	c.658T>C	p.Y220H	Human fibroblasts AG1521 (FASAY)	AFB1-25	Mutations identified on RNA by FASAY	18725321	2818:842
3453	benz(a)anthracene-3,4-dione	g.7674197T>G	c.766A>C	p.T256P	Yeast reporter gene assay	BAQ74	None	18489080	3453:187
308	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7676267G>T	c.102C>A	p.P34P	Hupki-XPAnull MEF	XN-BP-229	None	25847421	308:882
2462	anti-B(a)PDE	g.7674944C>G	c.587G>C	p.R196P	Yeast reporter gene assay	AM47	None	18489080	2462:205
2462	B(a)P-1,6 dione	g.7674944C>G	c.587G>C	p.R196P	Yeast reporter gene assay	1,6-9	None	22768918	2462:343
2462	B(a)P-1,6 dione	g.7674944C>G	c.587G>C	p.R196P	Yeast reporter gene assay	1,6-20	None	22768918	2462:348
2462	benz(a)anthracene-3,4-dione	g.7674944C>G	c.587G>C	p.R196P	Yeast reporter gene assay	BAQ-24	None	22768918	2462:433
2462	dimethylbenz(a)anthracene-3,4-dione	g.7674944C>G	c.587G>C	p.R196P	Yeast reporter gene assay	DB-8	None	22768918	2462:481
2707	aristolochic acid	g.7674893C>G	c.638G>C	p.R213P	Hupki MEF	L157 HUF (P/P)	None	19030178	2707:23
1815	anti-B(a)PDE	g.7675145C>G	c.467G>C	p.R156P	Yeast reporter gene assay	AM38	None	18489080	1815:203
1815	anti-B(a)PDE	g.7675145C>G	c.467G>C	p.R156P	Yeast reporter gene assay	F26	None	18489080	1815:212
1509	spontaneous immortalization	g.7675200C>G	c.412G>C	p.A138P	Hupki MEF	HUF-CO-J-204	None	18765419	1509:115
1509	spontaneous immortalization	g.7675200C>G	c.412G>C	p.A138P	Hupki MEF	HUF-CO-15	None	20118236	1509:133
1509	spontaneous immortalization	g.7675200C>G	c.412G>C	p.A138P	Hupki MEF	HUF-CO-16	None	20118236	1509:134
1509	spontaneous immortalization	g.7675200C>G	c.412G>C	p.A138P	Hupki MEF	XW-C-115	None	25847421	1509:913
2345	anti-B(a)PDE	g.7674966C>G	c.565G>C	p.A189P	Yeast reporter gene assay	F-25	None	22768918	2345:519
2246	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675070C>G	c.542G>C	p.R181P	Hupki MEF	XW-BP-26	None	25847421	2246:866
1876	aristolochic acid	g.7675137C>G	c.475G>C	p.A159P	Hupki MEF	L104 HUF (R/P)	None	19030178	1876:8
1876	spontaneous immortalization	g.7675137C>G	c.475G>C	p.A159P	Hupki MEF	HUF-CO-20	None	20118236	1876:138
1876	B(a)P radical cations	g.7675137C>G	c.475G>C	p.A159P	Yeast reporter gene assay	RC-34	None	22768918	1876:337
1744	B(a)P radical cations	g.7675156C>G	c.456G>C	p.P152P	Yeast reporter gene assay	RC-11	None	22768918	1744:314
3786	dimethylbenz(a)anthracene-3,4-dione	g.7673794C>G	c.826G>C	p.A276P	Yeast reporter gene assay	DB30	None	18489080	3786:194
3904	anti-B(a)PDE	g.7673772C>G	c.848G>C	p.R283P	Yeast reporter gene assay	F8	None	18489080	3904:201
1905	spontaneous immortalization	g.7675131C>G	c.481G>C	p.A161P	Hupki MEF	HUF-CO-22	None	20118236	1905:140
1905	3-nitrobenzanthrone	g.7675131C>G	c.481G>C	p.A161P	Hupki MEF	XW-3N-14	None	26723900	1905:917
1862	B(a)P (benzo(a)Pyrene)	g.7675139C>G	c.473G>C	p.R158P	Hupki MEF	HUF-BaP-4	None	15805253	1862:63
1862	anti-B(a)PDE	g.7675139C>G	c.473G>C	p.R158P	Yeast reporter gene assay	F22	None	18489080	1862:197
1383	B(a)P-7,8-dione	g.7675223A>G	c.389T>C	p.L130P	Yeast reporter gene assay	OGG1-6	OGG1 knock-out yeast	23117049	1383:644
1334	B(a)P-1,6 dione	g.7675233A>G	c.379T>C	p.S127P	Yeast reporter gene assay	1,6-33	None	22768918	1334:353
1334	B(a)P (benzo(a)Pyrene)	g.7675233A>G	c.379T>C	p.S127P	Human fibroblasts AG1521 (FASAY)	BaP-5	Mutations identified on RNA by FASAY	22319594	1334:833
3392	benzene	g.7674208A>G	c.755T>C	p.L252P	A549 human lung cell line	BIL15-BZ15	Mutations identified on RNA by FASAY	19862502	3392:953
3392	benzene	g.7674208A>G	c.755T>C	p.L252P	A549 human lung cell line	BIL15-BZ16	Mutations identified on RNA by FASAY	19862502	3392:954
1607	B(a)P radical cations	g.7675181T>G	c.431A>C	p.Q144P	Yeast reporter gene assay	RC-19	None	22768918	1607:322
2044	B(a)P-7,8-dione	g.7675104T>G	c.508A>C	p.T170P	Yeast reporter gene assay	BPQ-A17	None	12067251	2044:259
3298	anti-B(a)PDE	g.7674220C>G	c.743G>C	p.R248P	Yeast reporter gene assay	anti-BPDE-22	None	12067251	3298:233
3298	anti-B(a)PDE	g.7674220C>G	c.743G>C	p.R248P	Yeast reporter gene assay	F-27	None	22768918	3298:525
3298	anti-B(a)PDE	g.7674220C>G	c.743G>C	p.R248P	Yeast reporter gene assay	Am-4	methylated TP53 gene	22768918	3298:548
3298	B(a)P (benzo(a)Pyrene)	g.7674220C>G	c.743G>C	p.R248P	Human fibroblasts AG1521 (FASAY)	BaP-21	Mutations identified on RNA by FASAY	22319594	3298:767
3604	spontaneous immortalization	g.7673826A>G	c.794T>C	p.L265P	Hupki MEF	HUF-CO-II11	None	15805253	3604:76
3604	spontaneous immortalization	g.7673826A>G	c.794T>C	p.L265P	Hupki MEF	HUF-CO-48	None	20118236	3604:166
3471	benzene	g.7674193A>G	c.770T>C	p.L257P	A549 human lung cell line	BIL15-BZ17	Mutations identified on RNA by FASAY	19862502	3471:955
1619	B(a)P-3,6 dione	g.7675178A>G	c.434T>C	p.L145P	Yeast reporter gene assay	3,6-20	None	22768918	1619:382
1619	B(a)P-7,8-dione	g.7675178A>G	c.434T>C	p.L145P	Yeast reporter gene assay	APN1-3	APN1 knock-out yeast	23117049	1619:706
1619	AFB1 (aflatoxin)	g.7675178A>G	c.434T>C	p.L145P	Human fibroblasts AG1521 (FASAY)	AFB1-11	Mutations identified on RNA by FASAY	18725321	1619:786
2673	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674900T>G	c.631A>C	p.T211P	Hupki-XPAnull MEF	XN-BP-278	None	25847421	2673:897
2223	3-nitrobenzanthrone	g.7675076T>G	c.536A>C	p.H179P	Hupki MEF	XW-3N-54	None	26723900	2223:923
2409	B(a)P-7,8-dione	g.7674953T>G	c.578A>C	p.H193P	Yeast reporter gene assay	BPQ-A39	None	12067251	2409:265
4351	dimethylbenz(a)anthracene-3,4-dione	g.7673580G>A	c.948C>T	p.P316P	Yeast reporter gene assay	DB-45	None	22768918	4351:507
2537	B(a)P-7,8-dione	g.7674926C>G	c.605G>C	p.R202P	Yeast reporter gene assay	WT-35Z	Wild-type yeast	23117049	2537:616
1133	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7676040C>G	c.329G>C	p.R110P	Hupki-XPAnull MEF	XN-BP-201	None	25847421	1133:884
3738	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673802C>G	c.818G>C	p.R273P	Hupki-XPAnull MEF	XN-BP-274	None	25847421	3738:905
1255	B(a)P-3,6 dione	g.7676008A>G	c.361T>C	p.S121P	Yeast reporter gene assay	3,6-25	None	22768918	1255:383
2430	AFB1 (aflatoxin)	g.7674950A>G	c.581T>C	p.L194P	Human fibroblasts AG1521 (FASAY)	AFB1-21	Mutations identified on RNA by FASAY	18725321	2430:793
1818	B(a)P-3,6 dione	g.7675144G>T	c.468C>A	p.R156R	Yeast reporter gene assay	3,6-68	None	22768918	1818:392
1818	anti-B(a)PDE	g.7675144G>T	c.468C>A	p.R156R	Yeast reporter gene assay	Am-18	methylated TP53 gene	22768918	1818:550
3303	UV radiation	g.7674219C>T	c.744G>A	p.R248R	Hupki skin	UV-2	None	11719445	3303:52
3591	B(a)P-7,8-dione	g.7673829A>C	c.791T>G	p.L264R	Yeast reporter gene assay	BPQ-A18	None	12067251	3591:287
2207	acetaldehyde	g.7675079T>C	c.533A>G	p.H178R	Human fibroblasts AG1521 (FASAY)	Ac-11	Mutations identified on RNA by FASAY	18242117	2207:814
1722	B(a)P-7,8-dione	g.7675160G>C	c.452C>G	p.P151R	Yeast reporter gene assay	WT-9A	Wild-type yeast	23117049	1722:588
1722	B(a)P-7,8-dione	g.7675160G>C	c.452C>G	p.P151R	Yeast reporter gene assay	APN1-45	APN1 knock-out yeast	23117049	1722:739
3237	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674230C>G	c.733G>C	p.G245R	Hupki MEF	XW-BP-42	None	25847421	3237:872
3237	3-nitrobenzanthrone	g.7674230C>G	c.733G>C	p.G245R	Hupki-XPAnull MEF	XN-3N-136	None	26723900	3237:932
1458	B(a)P-7,8-dione	g.7675209A>G	c.403T>C	p.C135R	Yeast reporter gene assay	BPQ-A4	None	12067251	1458:237
1458	benz(a)anthracene-3,4-dione	g.7675209A>G	c.403T>C	p.C135R	Yeast reporter gene assay	BAQ-16	None	22768918	1458:405
1558	B(a)P (benzo(a)Pyrene)	g.7675191A>G	c.421T>C	p.C141R	Human fibroblasts AG1521 (FASAY)	BaP-9	Mutations identified on RNA by FASAY	22319594	1558:756
1608	AFB1 (aflatoxin)	g.7675181T>C	c.431A>G	p.Q144R	Human fibroblasts AG1521 (FASAY)	AFB1-10	Mutations identified on RNA by FASAY	18725321	1608:785
1740	anti-B(a)PDE	g.7675157G>C	c.455C>G	p.P152R	Yeast reporter gene assay	F-6	None	22768918	1740:514
1740	anti-B(a)PDE	g.7675157G>C	c.455C>G	p.P152R	Yeast reporter gene assay	Am-4	methylated TP53 gene	22768918	1740:545
1740	anti-B(a)PDE	g.7675157G>C	c.455C>G	p.P152R	Yeast reporter gene assay	Am-5	methylated TP53 gene	22768918	1740:549
1210	anti-B(a)PDE	g.7676020C>G	c.349G>C	p.G117R	Yeast reporter gene assay	F-9	None	22768918	1210:511
3605	AFB1 (aflatoxin)	g.7673826A>C	c.794T>G	p.L265R	Human fibroblasts AG1521 (FASAY)	AFB1-36	Mutations identified on RNA by FASAY	18725321	3605:801
3605	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673826A>C	c.794T>G	p.L265R	Hupki-XPAnull MEF	XN-BP-299	None	25847421	3605:901
4137	acetaldehyde	g.7673724A>C	c.896T>G	p.L299R	Human fibroblasts AG1521 (FASAY)	Ac-40	Mutations identified on RNA by FASAY	18242117	4137:830
2224	aristolochic acid	g.7675076T>C	c.536A>G	p.H179R	Hupki MEF	L115 HUF (R/P)	None	19030178	2224:13
990	anti-B(a)PDE	g.7676076G>C	c.293C>G	p.P98R	Yeast reporter gene assay	Am-26	methylated TP53 gene	22768918	990:538
742	B(a)P-7,8-dione	g.7676145G>C	c.224C>G	p.P75R	Yeast reporter gene assay	WT-25	Wild-type yeast	23117049	742:596
3554	anti-B(a)PDE	g.7673836C>G	c.784G>C	p.G262R	Yeast reporter gene assay	anti-BPDE-18	None	12067251	3554:234
3767	benz(a)anthracene-3,4-dione	g.7673797A>G	c.823T>C	p.C275R	Yeast reporter gene assay	BAQ75	None	18489080	3767:190
3767	benz(a)anthracene-3,4-dione	g.7673797A>G	c.823T>C	p.C275R	Yeast reporter gene assay	BAQ-9	None	22768918	3767:448
3101	B(a)P-1,6 dione	g.7674251A>G	c.712T>C	p.C238R	Yeast reporter gene assay	1,6-7	None	22768918	3101:341
3101	B(a)P-1,6 dione	g.7674251A>G	c.712T>C	p.C238R	Yeast reporter gene assay	1,6-10	None	22768918	3101:344
3101	dimethylbenz(a)anthracene-3,4-dione	g.7674251A>G	c.712T>C	p.C238R	Yeast reporter gene assay	DB-35	None	22768918	3101:491
2431	3-nitrobenzanthrone	g.7674950A>C	c.581T>G	p.L194R	Hupki MEF	XW-3N-15	None	26723900	2431:924
2708	benz(a)anthracene-3,4-dione	g.7674893C>A	c.638G>T	p.R213L	Yeast reporter gene assay	BAQ-19	None	22768918	2708:438
2708	benz(a)anthracene-3,4-dione	g.7674893C>A	c.638G>T	p.R213L	Yeast reporter gene assay	BAQ-11	None	22768918	2708:439
2708	dimethylbenz(a)anthracene-3,4-dione	g.7674893C>A	c.638G>T	p.R213L	Yeast reporter gene assay	DB-42	None	22768918	2708:484
2708	B(a)P-7,8-dione	g.7674893C>A	c.638G>T	p.R213L	Yeast reporter gene assay	WT-64Z	Wild-type yeast	23117049	2708:629
2708	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674893C>A	c.638G>T	p.R213L	Hupki MEF	XW-BP-50	None	25847421	2708:870
4229	dimethylbenz(a)anthracene-3,4-dione	g.7673703C>A	c.917G>T	p.R306L	Yeast reporter gene assay	DB-55	None	22768918	4229:506
2463	3-nitrobenzanthrone	g.7674944C>A	c.587G>T	p.R196L	Hupki MEF	HUF-3NBA-J-226	None	18765419	2463:87
2463	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674944C>A	c.587G>T	p.R196L	Hupki MEF	XW-BP-17	None	25847421	2463:868
2190	B(a)P-1,6 dione	g.7675082G>A	c.530C>T	p.P177L	Yeast reporter gene assay	1,6-11	None	22768918	2190:345
2190	B(a)P-7,8-dione	g.7675082G>A	c.530C>T	p.P177L	Yeast reporter gene assay	APN1-1	APN1 knock-out yeast	23117049	2190:704
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	WT-63Z	Wild-type yeast	23117049	3349:628
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-25Z	OGG1 knock-out yeast	23117049	3349:660
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-26Z	OGG1 knock-out yeast	23117049	3349:661
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-27Z	OGG1 knock-out yeast	23117049	3349:662
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-30Z	OGG1 knock-out yeast	23117049	3349:663
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-41Z	OGG1 knock-out yeast	23117049	3349:673
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-46Z	OGG1 knock-out yeast	23117049	3349:676
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-51Z	OGG1 knock-out yeast	23117049	3349:678
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-54Z	OGG1 knock-out yeast	23117049	3349:680
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-59Z	OGG1 knock-out yeast	23117049	3349:684
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-65Z	OGG1 knock-out yeast	23117049	3349:689
3349	B(a)P-7,8-dione	g.7674214G>A	c.749C>T	p.P250L	Yeast reporter gene assay	OGG1-76Z	OGG1 knock-out yeast	23117049	3349:700
1723	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675160G>A	c.452C>T	p.P151L	Yeast reporter gene assay	MNNG-3	None	12067251	1723:219
1723	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675160G>A	c.452C>T	p.P151L	Yeast reporter gene assay	MNNG-27	None	12067251	1723:227
1723	B(a)P-3,6 dione	g.7675160G>A	c.452C>T	p.P151L	Yeast reporter gene assay	3,6-13	None	22768918	1723:376
1723	acetaldehyde	g.7675160G>A	c.452C>T	p.P151L	Human fibroblasts AG1521 (FASAY)	Ac-9	Mutations identified on RNA by FASAY	18242117	1723:812
1622	B(a)P-7,8-dione	g.7675177C>G	c.435G>C	p.L145L	Yeast reporter gene assay	APN1-18A	APN1 knock-out yeast	23117049	1622:718
2145	dimethylbenz(a)anthracene-3,4-dione	g.7675088C>A	c.524G>T	p.R175L	Yeast reporter gene assay	DB-46	None	22768918	2145:457
2145	3-nitrobenzanthrone	g.7675088C>A	c.524G>T	p.R175L	Hupki MEF	XW-3N-55	None	26723900	2145:920
3905	benz(a)anthracene-3,4-dione	g.7673772C>A	c.848G>T	p.R283L	Yeast reporter gene assay	BAQ-52	None	22768918	3905:452
1816	B(a)P-7,8-dione	g.7675145C>A	c.467G>T	p.R156L	Yeast reporter gene assay	APN1-22	APN1 knock-out yeast	23117049	1816:722
1863	B(a)P (benzo(a)Pyrene)	g.7675139C>A	c.473G>T	p.R158L	Hupki MEF	HUF-BaP-28	None	15805253	1863:69
1863	B(a)P-3,6 dione	g.7675139C>A	c.473G>T	p.R158L	Yeast reporter gene assay	3,6-39	None	22768918	1863:385
1863	B(a)P-7,8-dione	g.7675139C>A	c.473G>T	p.R158L	Yeast reporter gene assay	OGG1-73ZA	OGG1 knock-out yeast	23117049	1863:696
1863	B(a)P-7,8-dione	g.7675139C>A	c.473G>T	p.R158L	Yeast reporter gene assay	APN1-2	APN1 knock-out yeast	23117049	1863:705
1863	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675139C>A	c.473G>T	p.R158L	Hupki-XPAnull MEF	XN-BP-225	None	25847421	1863:891
1863	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675139C>A	c.473G>T	p.R158L	Hupki-XPAnull MEF	XN-BP-228	None	25847421	1863:892
1863	3-nitrobenzanthrone	g.7675139C>A	c.473G>T	p.R158L	Hupki MEF	XW-3N-59	None	26723900	1863:916
1056	aristolochic acid	g.7676058T>A	c.311A>T	p.Q104L	Hupki MEF	L99 HUF (R/P)	None	19030178	1056:6
1741	B(a)P-7,8-dione	g.7675157G>A	c.455C>T	p.P152L	Yeast reporter gene assay	BPQ-BQ10	None	12067251	1741:247
1741	B(a)P radical cations	g.7675157G>A	c.455C>T	p.P152L	Yeast reporter gene assay	RC-13	None	22768918	1741:316
1741	B(a)P radical cations	g.7675157G>A	c.455C>T	p.P152L	Yeast reporter gene assay	RC-14	None	22768918	1741:317
1741	B(a)P radical cations	g.7675157G>A	c.455C>T	p.P152L	Yeast reporter gene assay	RC-17	None	22768918	1741:320
1741	B(a)P (benzo(a)Pyrene)	g.7675157G>A	c.455C>T	p.P152L	Human fibroblasts AG1521 (FASAY)	BaP-10	Mutations identified on RNA by FASAY	22319594	1741:757
2095	B(a)P-7,8-dione	g.7675095C>G	c.517G>C	p.V173L	Yeast reporter gene assay	WT-11	Wild-type yeast	23117049	2095:590
2755	spontaneous immortalization	g.7674885C>G	c.646G>C	p.V216L	Hupki MEF	HUF-CO-32	None	20118236	2755:150
3886	B(a)P-7,8-dione	g.7673775C>A	c.845G>T	p.R282L	Yeast reporter gene assay	OGG1-74ZA	OGG1 knock-out yeast	23117049	3886:697
3299	dimethylbenz(a)anthracene-3,4-dione	g.7674220C>A	c.743G>T	p.R248L	Yeast reporter gene assay	DB24	None	18489080	3299:208
3299	dimethylbenz(a)anthracene-3,4-dione	g.7674220C>A	c.743G>T	p.R248L	Yeast reporter gene assay	DB31	None	18489080	3299:210
3299	dimethylbenz(a)anthracene-3,4-dione	g.7674220C>A	c.743G>T	p.R248L	Yeast reporter gene assay	DB-63	None	22768918	3299:498
3299	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674220C>A	c.743G>T	p.R248L	Hupki MEF	XW-BP-95	None	25847421	3299:875
3636	B(a)P-7,8-dione	g.7673820C>A	c.800G>T	p.R267L	Yeast reporter gene assay	BPQ-A45	None	12067251	3636:288
3636	benz(a)anthracene-3,4-dione	g.7673820C>A	c.800G>T	p.R267L	Yeast reporter gene assay	BAQ-8	None	22768918	3636:447
3636	dimethylbenz(a)anthracene-3,4-dione	g.7673820C>A	c.800G>T	p.R267L	Yeast reporter gene assay	DB-37	None	22768918	3636:500
3636	anti-B(a)PDE	g.7673820C>A	c.800G>T	p.R267L	Yeast reporter gene assay	F-24	None	22768918	3636:527
2411	aristolochic acid	g.7674953T>A	c.578A>T	p.H193L	Hupki MEF	L12 HUF (R/R)	None	19030178	2411:33
3817	UV radiation	g.7673787G>A	c.833C>T	p.P278L	Hupki skin	UV-8	None	11719445	3817:58
3817	acetaldehyde	g.7673787G>A	c.833C>T	p.P278L	Human fibroblasts AG1521 (FASAY)	Ac-29	Mutations identified on RNA by FASAY	18242117	3817:824
3817	acetaldehyde	g.7673787G>A	c.833C>T	p.P278L	Human fibroblasts AG1521 (FASAY)	Ac-30	Mutations identified on RNA by FASAY	18242117	3817:856
2363	B(a)P-7,8-dione	g.7674962G>A	c.569C>T	p.P190L	Yeast reporter gene assay	WT-12P	Wild-type yeast	23117049	2363:600
2363	B(a)P-7,8-dione	g.7674962G>A	c.569C>T	p.P190L	Yeast reporter gene assay	WT-31P	Wild-type yeast	23117049	2363:608
2858	B(a)P-3,6 dione	g.7674863G>A	c.668C>T	p.P223L	Yeast reporter gene assay	3,6-69	None	22768918	2858:394
1356	B(a)P (benzo(a)Pyrene)	g.7675229G>A	c.383C>T	p.P128L	Human fibroblasts AG1521 (FASAY)	BaP-7	Mutations identified on RNA by FASAY	22319594	1356:754
1356	acetaldehyde	g.7675229G>A	c.383C>T	p.P128L	Human fibroblasts AG1521 (FASAY)	Ac-7	Mutations identified on RNA by FASAY	18242117	1356:810
3739	3-nitrobenzanthrone	g.7673802C>A	c.818G>T	p.R273L	Hupki MEF	HUF-3NBA-J-225	None	18765419	3739:100
3739	B(a)P-7,8-dione	g.7673802C>A	c.818G>T	p.R273L	Yeast reporter gene assay	BPQ-A19	None	12067251	3739:289
3739	B(a)P-7,8-dione	g.7673802C>A	c.818G>T	p.R273L	Yeast reporter gene assay	APN1-23B	APN1 knock-out yeast	23117049	3739:724
3739	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673802C>A	c.818G>T	p.R273L	Hupki MEF	XW-BP-6	None	25847421	3739:878
3739	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673802C>A	c.818G>T	p.R273L	Hupki MEF	XW-BP-63	None	25847421	3739:879
3739	3-nitrobenzanthrone	g.7673802C>A	c.818G>T	p.R273L	Hupki-XPAnull MEF	XN-3N-105	None	26723900	3739:935
3739	benzene	g.7673802C>A	c.818G>T	p.R273L	A549 human lung cell line	BIL15-BZ18	Mutations identified on RNA by FASAY	19862502	3739:956
2339	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674967C>A	c.564G>T	p.L188L	Hupki-XPAnull MEF	XN-BP-206	None	25847421	2339:894
3621	B(a)P-7,8-dione	g.7673823C>T	c.797G>A	p.G266E	Yeast reporter gene assay	OGG1-53Z	OGG1 knock-out yeast	23117049	3621:679
2875	B(a)P (benzo(a)Pyrene)	g.7674859C>T	c.672G>A	p.E224E	Hupki MEF	HUF-BaP-16	None	15805253	2875:67
2875	benz(a)anthracene-3,4-dione	g.7674859C>T	c.672G>A	p.E224E	Yeast reporter gene assay	BAQ-56	None	22768918	2875:442
2499	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674935C>T	c.596G>A	p.G199E	Yeast reporter gene assay	MNNG-6	None	12067251	2499:221
2499	benz(a)anthracene-3,4-dione	g.7674935C>T	c.596G>A	p.G199E	Yeast reporter gene assay	BAQ-65	None	22768918	2499:435
2499	benz(a)anthracene-3,4-dione	g.7674935C>T	c.596G>A	p.G199E	Yeast reporter gene assay	BAQ-61	None	22768918	2499:436
4445	B(a)P-7,8-dione	g.7673556A>T	c.972T>A	p.D324E	Yeast reporter gene assay	OGG1-78ZB	OGG1 knock-out yeast	23117049	4445:702
3494	aristolochic acid	g.7674189T>G	c.774A>C	p.E258D	Hupki MEF	L114 HUF (R/P)	None	19030178	3494:12
3494	spontaneous immortalization	g.7674189T>G	c.774A>C	p.E258D	Hupki MEF	HUF-CO-47	None	20118236	3494:165
3040	B(a)P-7,8-dione	g.7674260T>C	c.703A>G	p.N235D	Yeast reporter gene assay	BPQ-BPQ2	None	12067251	3040:258
3126	aristolochic acid	g.7674248T>C	c.715A>G	p.N239D	Hupki MEF	L95 HUF (R/P)	None	19030178	3126:1
3126	dimethylbenz(a)anthracene-3,4-dione	g.7674248T>C	c.715A>G	p.N239D	Yeast reporter gene assay	DB3	None	18489080	3126:191
3277	B(a)P-7,8-dione	g.7674224T>C	c.739A>G	p.N247D	Yeast reporter gene assay	APN1-14	APN1 knock-out yeast	23117049	3277:714
3277	acetaldehyde	g.7674224T>C	c.739A>G	p.N247D	Human fibroblasts AG1521 (FASAY)	Ac-17	Mutations identified on RNA by FASAY	18242117	3277:818
1911	B(a)P radical cations	g.7675130G>T	c.482C>A	p.A161D	Yeast reporter gene assay	RC-26	None	22768918	1911:329
1911	dimethylbenz(a)anthracene-3,4-dione	g.7675130G>T	c.482C>A	p.A161D	Yeast reporter gene assay	DB-6	None	22768918	1911:471
1911	B(a)P-7,8-dione	g.7675130G>T	c.482C>A	p.A161D	Yeast reporter gene assay	OGG1-2B	OGG1 knock-out yeast	23117049	1911:640
1911	B(a)P-7,8-dione	g.7675130G>T	c.482C>A	p.A161D	Yeast reporter gene assay	OGG1-4	OGG1 knock-out yeast	23117049	1911:642
1911	B(a)P-7,8-dione	g.7675130G>T	c.482C>A	p.A161D	Yeast reporter gene assay	OGG1-30	OGG1 knock-out yeast	23117049	1911:658
3789	B(a)P-1,6 dione	g.7673793G>T	c.827C>A	p.A276D	Yeast reporter gene assay	1,6-91	None	22768918	3789:370
1512	B(a)P-7,8-dione	g.7675199G>T	c.413C>A	p.A138D	Yeast reporter gene assay	BPQ-I7	None	12067251	1512:241
1367	AFB1 (aflatoxin)	g.7675226G>T	c.386C>A	p.A129D	Human fibroblasts AG1521 (FASAY)	AFB1-8	Mutations identified on RNA by FASAY	18725321	1367:783
2202	anti-B(a)PDE	g.7675080G>C	c.532C>G	p.H178D	Yeast reporter gene assay	F4	None	18489080	2202:199
2202	anti-B(a)PDE	g.7675080G>C	c.532C>G	p.H178D	Yeast reporter gene assay	F-23	None	22768918	2202:516
4105	B(a)P radical cations	g.7673731G>C	c.889C>G	p.H297D	Yeast reporter gene assay	RC-6	None	22768918	4105:309
3005	anti-B(a)PDE	g.7674266G>C	c.697C>G	p.H233D	Yeast reporter gene assay	Am-28	methylated TP53 gene	22768918	3005:563
3220	B(a)P-7,8-dione	g.7674232C>T	c.731G>A	p.G244D	Yeast reporter gene assay	BPQ-I11	None	12067251	3220:278
3220	B(a)P-7,8-dione	g.7674232C>T	c.731G>A	p.G244D	Yeast reporter gene assay	BPQ-A6	None	12067251	3220:279
3220	B(a)P-7,8-dione	g.7674232C>T	c.731G>A	p.G244D	Yeast reporter gene assay	BPQ-A58	None	12067251	3220:280
3220	AFB1 (aflatoxin)	g.7674232C>T	c.731G>A	p.G244D	Human fibroblasts AG1521 (FASAY)	AFB1-27	Mutations identified on RNA by FASAY	18725321	3220:797
3220	AFB1 (aflatoxin)	g.7674232C>T	c.731G>A	p.G244D	Human fibroblasts AG1521 (FASAY)	AFB1-28	Mutations identified on RNA by FASAY	18725321	3220:843
3244	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674229C>T	c.734G>A	p.G245D	Hupki MEF	MNNG 100 HUF (R/P)	None	19030178	3244:46
3244	spontaneous immortalization	g.7674229C>T	c.734G>A	p.G245D	Hupki MEF	HUF-CO-35	None	20118236	3244:153
3244	spontaneous immortalization	g.7674229C>T	c.734G>A	p.G245D	Hupki MEF	HUF-CO-36	None	20118236	3244:154
3244	dimethylbenz(a)anthracene-3,4-dione	g.7674229C>T	c.734G>A	p.G245D	Yeast reporter gene assay	DB-39	None	22768918	3244:497
2901	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674286C>T	c.677G>A	p.G226D	Yeast reporter gene assay	MNNG-10	None	12067251	2901:223
2876	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674859C>G	c.672G>C	p.E224D	Hupki MEF	XW-BP-83	None	25847421	2876:871
3022	B(a)P radical cations	g.7674263A>C	c.700T>G	p.Y234D	Yeast reporter gene assay	RC-33	None	22768918	3022:336
4727	B(a)P radical cations	g.7670658T>C	c.1051A>G	p.K351E	Yeast reporter gene assay	RC-35	None	22768918	4727:338
4020	B(a)P-7,8-dione	g.7673749T>C	c.871A>G	p.K291E	Yeast reporter gene assay	APN1-15	APN1 knock-out yeast	23117049	4020:715
1526	B(a)P-7,8-dione	g.7675197T>C	c.415A>G	p.K139E	Yeast reporter gene assay	BPQ-A10	None	12067251	1526:242
3866	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673777G>C	c.843C>G	p.D281E	Hupki MEF	MNNG 113 HUF (R/P)	None	19030178	3866:48
3866	spontaneous immortalization	g.7673777G>C	c.843C>G	p.D281E	Hupki MEF	HUF-CO-58	None	20118236	3866:176
3866	spontaneous immortalization	g.7673777G>C	c.843C>G	p.D281E	Hupki MEF	HUF-CO-59	None	20118236	3866:177
3866	spontaneous immortalization	g.7673777G>C	c.843C>G	p.D281E	Hupki MEF	HUF-CO-60	None	20118236	3866:178
2002	benz(a)anthracene-3,4-dione	g.7675113G>C	c.499C>G	p.Q167E	Yeast reporter gene assay	BAQ-73	None	22768918	2002:416
3833	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673784C>T	c.836G>A	p.G279E	Yeast reporter gene assay	MNNG-11	None	12067251	3833:224
3833	B(a)P-7,8-dione	g.7673784C>T	c.836G>A	p.G279E	Yeast reporter gene assay	BPQ-A43	None	12067251	3833:291
3833	B(a)P (benzo(a)Pyrene)	g.7673784C>T	c.836G>A	p.G279E	Human fibroblasts AG1521 (FASAY)	BaP-31	Mutations identified on RNA by FASAY	22319594	3833:773
1212	anti-B(a)PDE	g.7676019C>T	c.350G>A	p.G117E	Yeast reporter gene assay	Am-22	methylated TP53 gene	22768918	1212:539
4179	B(a)P-3,6 dione	g.7673715C>T	c.905G>A	p.G302E	Yeast reporter gene assay	3,6-14	None	22768918	4179:377
2760	B(a)P-7,8-dione	g.7674884A>T	c.647T>A	p.V216E	Yeast reporter gene assay	WT-50Z	Wild-type yeast	23117049	2760:625
1589	anti-B(a)PDE	g.7675184A>T	c.428T>A	p.V143E	Yeast reporter gene assay	Am-42	methylated TP53 gene	22768918	1589:544
3976	B(a)P-1,6 dione	g.7673758T>C	c.862A>G	p.N288D	Yeast reporter gene assay	1,6-1	None	22768918	3976:339
3976	B(a)P (benzo(a)Pyrene)	g.7673758T>C	c.862A>G	p.N288D	Human fibroblasts AG1521 (FASAY)	BaP-36	Mutations identified on RNA by FASAY	22319594	3976:777
3559	B(a)P-7,8-dione	g.7673835C>T	c.785G>A	p.G262D	Yeast reporter gene assay	BPQ-BQ23	None	12067251	3559:286
3559	B(a)P-7,8-dione	g.7673835C>T	c.785G>A	p.G262D	Yeast reporter gene assay	APN1-26	APN1 knock-out yeast	23117049	3559:728
3559	B(a)P-7,8-dione	g.7673835C>T	c.785G>A	p.G262D	Yeast reporter gene assay	APN1-28	APN1 knock-out yeast	23117049	3559:730
2072	acetaldehyde	g.7675099C>A	c.513G>T	p.E171D	Human fibroblasts AG1521 (FASAY)	Ac-10	Mutations identified on RNA by FASAY	18242117	2072:813
2877	B(a)P-7,8-dione	g.7674859C>A	c.672G>T	p.E224D	Yeast reporter gene assay	OGG1-67ZA	OGG1 knock-out yeast	23117049	2877:690
3706	B(a)P-7,8-dione	g.7673807C>A	c.813G>T	p.E271D	Yeast reporter gene assay	WT-28Z	Wild-type yeast	23117049	3706:613
3706	B(a)P (benzo(a)Pyrene)	g.7673807C>A	c.813G>T	p.E271D	Human fibroblasts AG1521 (FASAY)	BaP-28	Mutations identified on RNA by FASAY	22319594	3706:770
2239	anti-B(a)PDE	g.7675072C>A	c.540G>T	p.E180D	Yeast reporter gene assay	P-2	None	22768918	2239:517
3942	B(a)P-7,8-dione	g.7673765C>A	c.855G>T	p.E285D	Yeast reporter gene assay	OGG1-67ZB	OGG1 knock-out yeast	23117049	3942:691
3942	B(a)P (benzo(a)Pyrene)	g.7673765C>A	c.855G>T	p.E285D	Human fibroblasts AG1521 (FASAY)	BaP-35	Mutations identified on RNA by FASAY	22319594	3942:776
1699	dimethylbenz(a)anthracene-3,4-dione	g.7675164T>C	c.448A>G	p.T150A	Yeast reporter gene assay	DB-58	None	22768918	1699:465
1717	B(a)P radical cations	g.7675161G>C	c.451C>G	p.P151A	Yeast reporter gene assay	RC-1	None	22768918	1717:304
1717	benz(a)anthracene-3,4-dione	g.7675161G>C	c.451C>G	p.P151A	Yeast reporter gene assay	BAQ-38	None	22768918	1717:410
4147	B(a)P-7,8-dione	g.7673722G>C	c.898C>G	p.P300A	Yeast reporter gene assay	BPQ-A15	None	12067251	4147:271
3245	aristolochic acid	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	L159 HUF (P/P)	None	19030178	3245:25
3245	3-nitrobenzanthrone	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-3NBA-J-102	None	18765419	3245:94
3245	3-nitrobenzanthrone	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-3NBA-J-229	None	18765419	3245:95
3245	N-hydroxy-3-aminobenzanthrone	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-NOH3A-A-51	None	18765419	3245:111
3245	spontaneous immortalization	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-CO-37	None	20118236	3245:155
3245	spontaneous immortalization	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-CO-38	None	20118236	3245:156
3245	spontaneous immortalization	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-CO-39	None	20118236	3245:157
3245	spontaneous immortalization	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-CO-40	None	20118236	3245:158
3245	spontaneous immortalization	g.7674229C>G	c.734G>C	p.G245A	Hupki MEF	HUF-CO-41	None	20118236	3245:159
3221	3-nitrobenzanthrone	g.7674232C>G	c.731G>C	p.G244A	Hupki MEF	HUF-3NBA-J-229	None	18765419	3221:92
3221	3-nitrobenzanthrone	g.7674232C>G	c.731G>C	p.G244A	Hupki MEF	HUF-3NBA-J-230	None	18765419	3221:93
3221	N-hydroxy-3-aminobenzanthrone	g.7674232C>G	c.731G>C	p.G244A	Hupki MEF	HUF-NOH3A-A-42	None	18765419	3221:110
3221	3-nitrobenzanthrone	g.7674232C>G	c.731G>C	p.G244A	Hupki-XPAnull MEF	XN-3N-137	None	26723900	3221:931
1066	spontaneous immortalization	g.7676055C>G	c.314G>C	p.G105A	Hupki MEF	HUF-CO-1	None	20118236	1066:119
2045	benz(a)anthracene-3,4-dione	g.7675104T>C	c.508A>G	p.T170A	Yeast reporter gene assay	BAQ-12	None	22768918	2045:420
2045	dimethylbenz(a)anthracene-3,4-dione	g.7675104T>C	c.508A>G	p.T170A	Yeast reporter gene assay	DB-9	None	22768918	2045:473
2045	AFB1 (aflatoxin)	g.7675104T>C	c.508A>G	p.T170A	Human fibroblasts AG1521 (FASAY)	AFB1-14	Mutations identified on RNA by FASAY	18725321	2045:789
2045	AFB1 (aflatoxin)	g.7675104T>C	c.508A>G	p.T170A	Human fibroblasts AG1521 (FASAY)	AFB1-15	Mutations identified on RNA by FASAY	18725321	2045:838
3834	anti-B(a)PDE	g.7673784C>G	c.836G>C	p.G279A	Yeast reporter gene assay	F11	None	18489080	3834:200
3834	anti-B(a)PDE	g.7673784C>G	c.836G>C	p.G279A	Yeast reporter gene assay	AM6	None	18489080	3834:207
1590	B(a)P-7,8-dione	g.7675184A>G	c.428T>C	p.V143A	Yeast reporter gene assay	WT-73Z	Wild-type yeast	23117049	1590:634
2794	B(a)P-7,8-dione	g.7674878A>G	c.653T>C	p.V218A	Yeast reporter gene assay	APN1-25B	APN1 knock-out yeast	23117049	2794:727
2794	B(a)P-7,8-dione	g.7674878A>G	c.653T>C	p.V218A	Yeast reporter gene assay	APN1-30B	APN1 knock-out yeast	23117049	2794:732
3844	B(a)P (benzo(a)Pyrene)	g.7673782T>C	c.838A>G	p.R280G	Hupki MEF	HUF-BaP-106	None	15805253	3844:70
3844	B(a)P (benzo(a)Pyrene)	g.7673782T>C	c.838A>G	p.R280G	Human fibroblasts AG1521 (FASAY)	BaP-32	Mutations identified on RNA by FASAY	22319594	3844:774
3953	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673763T>C	c.857A>G	p.E286G	Hupki MEF	XW-BP-38	None	25847421	3953:881
3225	B(a)P-7,8-dione	g.7674231G>T	c.732C>A	p.G244G	Yeast reporter gene assay	OGG1-63ZB	OGG1 knock-out yeast	23117049	3225:687
1159	B(a)P-7,8-dione	g.7676033G>T	c.336C>A	p.G112G	Yeast reporter gene assay	OGG1-57Z	OGG1 knock-out yeast	23117049	1159:683
2704	benz(a)anthracene-3,4-dione	g.7674894G>C	c.637C>G	p.R213G	Yeast reporter gene assay	BAQ15	None	18489080	2704:181
2457	B(a)P-7,8-dione	g.7674945G>C	c.586C>G	p.R196G	Yeast reporter gene assay	BPQ-A32	None	12067251	2457:266
2457	B(a)P radical cations	g.7674945G>C	c.586C>G	p.R196G	Yeast reporter gene assay	RC-4	None	22768918	2457:307
2457	anti-B(a)PDE	g.7674945G>C	c.586C>G	p.R196G	Yeast reporter gene assay	F-12	None	22768918	2457:512
2457	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674945G>C	c.586C>G	p.R196G	Hupki-XPAnull MEF	XN-BP-273	None	25847421	2457:896
3790	spontaneous immortalization	g.7673793G>C	c.827C>G	p.A276G	Hupki MEF	HUF-CO-54	None	20118236	3790:172
3790	B(a)P-7,8-dione	g.7673793G>C	c.827C>G	p.A276G	Yeast reporter gene assay	WT-41Z	Wild-type yeast	23117049	3790:620
1513	B(a)P (benzo(a)Pyrene)	g.7675199G>C	c.413C>G	p.A138G	Hupki MEF	HUF-BaP-4	None	15805253	1513:61
1810	anti-B(a)PDE	g.7675146G>C	c.466C>G	p.R156G	Yeast reporter gene assay	AM31	None	18489080	1810:202
1810	anti-B(a)PDE	g.7675146G>C	c.466C>G	p.R156G	Yeast reporter gene assay	Am-34	methylated TP53 gene	22768918	1810:551
1857	aristolochic acid	g.7675140G>C	c.472C>G	p.R158G	Hupki MEF	L9 HUF (R/R)	None	19030178	1857:29
1857	anti-B(a)PDE	g.7675140G>C	c.472C>G	p.R158G	Yeast reporter gene assay	AM41	None	18489080	1857:204
1912	spontaneous immortalization	g.7675130G>C	c.482C>G	p.A161G	Hupki MEF	HUF-CO-21	None	20118236	1912:139
1912	3-nitrobenzanthrone	g.7675130G>C	c.482C>G	p.A161G	Hupki MEF	XW-3N-15	None	26723900	1912:919
5084	B(a)P-7,8-dione	g.7669624C>G	c.1167G>C	p.G389G	Yeast reporter gene assay	APN1-41	APN1 knock-out yeast	23117049	5084:736
2162	B(a)P-7,8-dione	g.7675086A>C	c.526T>G	p.C176G	Yeast reporter gene assay	APN1-20	APN1 knock-out yeast	23117049	2162:721
2235	benz(a)anthracene-3,4-dione	g.7675073T>C	c.539A>G	p.E180G	Yeast reporter gene assay	BAQ-23	None	22768918	2235:419
3878	anti-B(a)PDE	g.7673776G>C	c.844C>G	p.R282G	Yeast reporter gene assay	Am-48	methylated TP53 gene	22768918	3878:568
3878	anti-B(a)PDE	g.7673776G>C	c.844C>G	p.R282G	Yeast reporter gene assay	Am-54	methylated TP53 gene	22768918	3878:569
3878	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673776G>C	c.844C>G	p.R282G	Hupki-XPAnull MEF	XN-BP-238	None	25847421	3878:909
2102	spontaneous immortalization	g.7675094A>C	c.518T>G	p.V173G	Hupki MEF	XW-C-137	None	25847421	2102:914
3729	spontaneous immortalization	g.7673803G>C	c.817C>G	p.R273G	Hupki MEF	HUF-CO-49	None	20118236	3729:167
3729	spontaneous immortalization	g.7673803G>C	c.817C>G	p.R273G	Hupki MEF	HUF-CO-50	None	20118236	3729:168
3729	B(a)P-3,6 dione	g.7673803G>C	c.817C>G	p.R273G	Yeast reporter gene assay	3,6-74	None	22768918	3729:399
3729	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673803G>C	c.817C>G	p.R273G	Hupki-XPAnull MEF	XN-BP-237	None	25847421	3729:904
1644	spontaneous immortalization	g.7675172A>C	c.440T>G	p.V147G	Hupki MEF	HUF-CO-J-220	None	18765419	1644:117
1644	spontaneous immortalization	g.7675172A>C	c.440T>G	p.V147G	Hupki MEF	HUF-CO-19	None	20118236	1644:137
1644	spontaneous immortalization	g.7675172A>C	c.440T>G	p.V147G	Hupki MEF	HUF-CO-62	None	20118236	1644:180
1644	spontaneous immortalization	g.7675172A>C	c.440T>G	p.V147G	Hupki MEF	HUF-CO-63	None	20118236	1644:216
1644	dimethylbenz(a)anthracene-3,4-dione	g.7675172A>C	c.440T>G	p.V147G	Yeast reporter gene assay	DB-36	None	22768918	1644:466
1644	benzene	g.7675172A>C	c.440T>G	p.V147G	A549 human lung cell line	BIL15-BZ6	Mutations identified on RNA by FASAY	19862502	1644:944
3768	benzene	g.7673797A>C	c.823T>G	p.C275G	A549 human lung cell line	BIL15-BZ19	Mutations identified on RNA by FASAY	19862502	3768:957
3954	aristolochic acid	g.7673763T>A	c.857A>T	p.E286V	Hupki MEF	L11 HUF (R/R)	None	19030178	3954:32
3717	B(a)P-7,8-dione	g.7673804C>T	c.816G>A	p.V272V	Yeast reporter gene assay	OGG1-33ZB	OGG1 knock-out yeast	23117049	3717:665
3368	benz(a)anthracene-3,4-dione	g.7674212T>C	c.751A>G	p.I251V	Yeast reporter gene assay	BAQ4	None	18489080	3368:186
3368	B(a)P radical cations	g.7674212T>C	c.751A>G	p.I251V	Yeast reporter gene assay	RC-18	None	22768918	3368:321
3368	B(a)P-7,8-dione	g.7674212T>C	c.751A>G	p.I251V	Yeast reporter gene assay	APN1-10	APN1 knock-out yeast	23117049	3368:711
3864	aristolochic acid	g.7673778T>A	c.842A>T	p.D281V	Hupki MEF	L10 HUF (R/R)	None	19030178	3864:31
1380	B(a)P-7,8-dione	g.7675224G>C	c.388C>G	p.L130V	Yeast reporter gene assay	BPQ-A11	None	12067251	1380:253
3791	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673793G>A	c.827C>T	p.A276V	Yeast reporter gene assay	MNNG-11	None	12067251	3791:303
3791	B(a)P-3,6 dione	g.7673793G>A	c.827C>T	p.A276V	Yeast reporter gene assay	3,6-12	None	22768918	3791:375
3791	B(a)P-3,6 dione	g.7673793G>A	c.827C>T	p.A276V	Yeast reporter gene assay	3,6-46	None	22768918	3791:387
3791	B(a)P-7,8-dione	g.7673793G>A	c.827C>T	p.A276V	Yeast reporter gene assay	WT-1P	Wild-type yeast	23117049	3791:597
3791	benzene	g.7673793G>A	c.827C>T	p.A276V	A549 human lung cell line	BIL15-BZ20	Mutations identified on RNA by FASAY	19862502	3791:958
1881	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675136G>A	c.476C>T	p.A159V	Hupki MEF	MNNG 88 HUF (R/P)	None	19030178	1881:43
2558	aristolochic acid	g.7674922C>G	c.609G>C	p.V203V	Hupki MEF	L16 HUF (R/R)	None	19030178	2558:37
1067	B(a)P-7,8-dione	g.7676055C>A	c.314G>T	p.G105V	Yeast reporter gene assay	WT-68Z	Wild-type yeast	23117049	1067:633
1774	aristolochic acid	g.7675151C>A	c.461G>T	p.G154V	Hupki MEF	L158 HUF (P/P)	None	19030178	1774:24
1774	B(a)P-7,8-dione	g.7675151C>A	c.461G>T	p.G154V	Yeast reporter gene assay	BPQ-A36	None	12067251	1774:248
1774	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675151C>A	c.461G>T	p.G154V	Hupki MEF	XW-BP-83	None	25847421	1774:864
3222	benz(a)anthracene-3,4-dione	g.7674232C>A	c.731G>T	p.G244V	Yeast reporter gene assay	BAQ22	None	18489080	3222:183
3222	benzene	g.7674232C>A	c.731G>T	p.G244V	A549 human lung cell line	BIL15-BZ13	Mutations identified on RNA by FASAY	19862502	3222:951
1166	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7676032A>C	c.337T>G	p.F113V	Hupki MEF	MNNG 114 HUF (R/P)	None	19030178	1166:49
1166	spontaneous immortalization	g.7676032A>C	c.337T>G	p.F113V	Hupki MEF	HUF-CO-2	None	20118236	1166:120
1166	spontaneous immortalization	g.7676032A>C	c.337T>G	p.F113V	Hupki MEF	HUF-CO-3	None	20118236	1166:121
1166	spontaneous immortalization	g.7676032A>C	c.337T>G	p.F113V	Hupki-XPAnull MEF	XN-C-325	None	25847421	1166:911
1166	spontaneous immortalization	g.7676032A>C	c.337T>G	p.F113V	Hupki-XPAnull MEF	XN-C-338	None	25847421	1166:912
3081	benzene	g.7674254T>C	c.709A>G	p.M237V	A549 human lung cell line	BIL15-BZ10	Mutations identified on RNA by FASAY	19862502	3081:948
3259	B(a)P-7,8-dione	g.7674227T>C	c.736A>G	p.M246V	Yeast reporter gene assay	OGG1-31	OGG1 knock-out yeast	23117049	3259:659
2236	dimethylbenz(a)anthracene-3,4-dione	g.7675073T>A	c.539A>T	p.E180V	Yeast reporter gene assay	DB-33	None	22768918	2236:477
1214	B(a)P-1,6 dione	g.7676019C>A	c.350G>T	p.G117V	Yeast reporter gene assay	1,6-71	None	22768918	1214:360
1214	B(a)P (benzo(a)Pyrene)	g.7676019C>A	c.350G>T	p.G117V	Human fibroblasts AG1521 (FASAY)	BaP-2	Mutations identified on RNA by FASAY	22319594	1214:750
2594	3-nitrobenzanthrone	g.7674915A>C	c.616T>G	p.L206V	Hupki MEF	HUF-3NBA-J-260	None	18765419	2594:89
1845	B(a)P (benzo(a)Pyrene)	g.7675141G>A	c.471C>T	p.V157V	Hupki MEF	HUF-BaP-4	None	15805253	1845:62
1845	B(a)P (benzo(a)Pyrene)	g.7675141G>A	c.471C>T	p.V157V	Hupki MEF	HUF-BaP-28	None	15805253	1845:68
1845	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675141G>A	c.471C>T	p.V157V	Hupki-XPAnull MEF	XN-BP-225	None	25847421	1845:889
3561	acetaldehyde	g.7673835C>A	c.785G>T	p.G262V	Human fibroblasts AG1521 (FASAY)	Ac-24	Mutations identified on RNA by FASAY	18242117	3561:821
1441	spontaneous immortalization	g.7675212A>C	c.400T>G	p.F134V	Hupki MEF	HUF-CO-6	None	20118236	1441:124
1441	spontaneous immortalization	g.7675212A>C	c.400T>G	p.F134V	Hupki MEF	HUF-CO-7	None	20118236	1441:125
3678	3-nitrobenzanthrone	g.7673812A>C	c.808T>G	p.F270V	Hupki MEF	HUF-3NBA-J-260	None	18765419	3678:99
4407	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673567T>A	c.961A>T	p.K321*	Hupki MEF	MNNG 84 HUF (R/P)	None	19030178	4407:41
1946	B(a)P (benzo(a)Pyrene)	g.7675123G>T	c.489C>A	p.Y163*	Human fibroblasts AG1521 (FASAY)	BaP-11	Mutations identified on RNA by FASAY	22319594	1946:758
3067	B(a)P-7,8-dione	g.7674255G>T	c.708C>A	p.Y236*	Yeast reporter gene assay	BPQ-A37	None	12067251	3067:274
3067	B(a)P-1,6 dione	g.7674255G>T	c.708C>A	p.Y236*	Yeast reporter gene assay	1,6-87	None	22768918	3067:367
3067	B(a)P-1,6 dione	g.7674255G>T	c.708C>A	p.Y236*	Yeast reporter gene assay	1,6-89	None	22768918	3067:368
3067	B(a)P-7,8-dione	g.7674255G>T	c.708C>A	p.Y236*	Yeast reporter gene assay	APN1-24	APN1 knock-out yeast	23117049	3067:725
2266	B(a)P-7,8-dione	g.7675064G>T	c.548C>A	p.S183*	Yeast reporter gene assay	BPQ-BQ25	None	12067251	2266:264
2266	B(a)P-7,8-dione	g.7675064G>T	c.548C>A	p.S183*	Yeast reporter gene assay	OGG1-36Z	OGG1 knock-out yeast	23117049	2266:667
3028	AFB1 (aflatoxin)	g.7674261G>T	c.702C>A	p.Y234*	Human fibroblasts AG1521 (FASAY)	AFB1-26	Mutations identified on RNA by FASAY	18725321	3028:796
1477	anti-B(a)PDE	g.7675206G>A	c.406C>T	p.Q136*	Yeast reporter gene assay	Am-57	methylated TP53 gene	22768918	1477:541
4462	B(a)P-7,8-dione	g.7673552C>A	c.976G>T	p.E326*	Yeast reporter gene assay	WT-33Z	Wild-type yeast	23117049	4462:615
2483	B(a)P-7,8-dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	BPQ-BQ27	None	12067251	2483:244
2483	B(a)P-7,8-dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	BPQ-A9	None	12067251	2483:267
2483	B(a)P-7,8-dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	BPQ-BQ6	None	12067251	2483:268
2483	B(a)P-1,6 dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	1,6-86	None	22768918	2483:366
2483	B(a)P-1,6 dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	1,6-90	None	22768918	2483:369
2483	dimethylbenz(a)anthracene-3,4-dione	g.7674939C>A	c.592G>T	p.E198*	Yeast reporter gene assay	DB-44	None	22768918	2483:482
1392	aristolochic acid	g.7675221T>A	c.391A>T	p.N131Y	Hupki MEF	L96 HUF (R/P)	None	19030178	1392:2
3168	B(a)P-7,8-dione	g.7674241G>T	c.722C>A	p.S241Y	Yeast reporter gene assay	WT-67ZA	Wild-type yeast	23117049	3168:631
3168	B(a)P-7,8-dione	g.7674241G>T	c.722C>A	p.S241Y	Yeast reporter gene assay	OGG1-29A	OGG1 knock-out yeast	23117049	3168:656
3168	B(a)P-7,8-dione	g.7674241G>T	c.722C>A	p.S241Y	Yeast reporter gene assay	OGG1-63ZA	OGG1 knock-out yeast	23117049	3168:686
1339	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675232G>T	c.380C>A	p.S127Y	Hupki-XPAnull MEF	XN-BP-294	None	25847421	1339:885
1684	B(a)P-7,8-dione	g.7675166G>T	c.446C>A	p.S149Y	Yeast reporter gene assay	BPQ-BQ27	None	12067251	1684:243
4106	benz(a)anthracene-3,4-dione	g.7673731G>A	c.889C>T	p.H297Y	Yeast reporter gene assay	BAQ-60	None	22768918	4106:431
4094	AFB1 (aflatoxin)	g.7673734G>A	c.886C>T	p.H296Y	Human fibroblasts AG1521 (FASAY)	AFB1-43	Mutations identified on RNA by FASAY	18725321	4094:808
3185	B(a)P-7,8-dione	g.7674238C>T	c.725G>A	p.C242Y	Yeast reporter gene assay	APN1-9	APN1 knock-out yeast	23117049	3185:710
3185	B(a)P-7,8-dione	g.7674238C>T	c.725G>A	p.C242Y	Yeast reporter gene assay	APN1-16	APN1 knock-out yeast	23117049	3185:716
3185	B(a)P (benzo(a)Pyrene)	g.7674238C>T	c.725G>A	p.C242Y	Human fibroblasts AG1521 (FASAY)	BaP-20	Mutations identified on RNA by FASAY	22319594	3185:766
3185	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674238C>T	c.725G>A	p.C242Y	Hupki-XPAnull MEF	XN-BP-265	None	25847421	3185:899
2166	spontaneous immortalization	g.7675085C>T	c.527G>A	p.C176Y	Hupki MEF	HUF-CO-28	None	20118236	2166:146
2166	B(a)P-7,8-dione	g.7675085C>T	c.527G>A	p.C176Y	Yeast reporter gene assay	OGG1-8	OGG1 knock-out yeast	23117049	2166:645
1562	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675190C>T	c.422G>A	p.C141Y	Hupki MEF	MNNG 115 HUF (R/P)	None	19030178	1562:50
3501	B(a)P-7,8-dione	g.7674188C>A	c.775G>T	p.D259Y	Yeast reporter gene assay	BPQ-A34	None	12067251	3501:285
3858	B(a)P-7,8-dione	g.7673779C>A	c.841G>T	p.D281Y	Yeast reporter gene assay	BPQ-BQ27	None	12067251	3858:245
3858	B(a)P-7,8-dione	g.7673779C>A	c.841G>T	p.D281Y	Yeast reporter gene assay	BPQ-B100	None	12067251	3858:293
3858	B(a)P radical cations	g.7673779C>A	c.841G>T	p.D281Y	Yeast reporter gene assay	RC-20	None	22768918	3858:323
3858	benz(a)anthracene-3,4-dione	g.7673779C>A	c.841G>T	p.D281Y	Yeast reporter gene assay	BAQ-57	None	22768918	3858:450
3858	benz(a)anthracene-3,4-dione	g.7673779C>A	c.841G>T	p.D281Y	Yeast reporter gene assay	BAQ-10	None	22768918	3858:451
4213	aristolochic acid	g.7673707T>A	c.913A>T	p.K305*	Hupki MEF	L97 HUF (R/P)	None	19030178	4213:4
4021	aristolochic acid	g.7673749T>A	c.871A>T	p.K291*	Hupki MEF	L96 HUF (R/P)	None	19030178	4021:3
1956	aristolochic acid	g.7675122T>A	c.490A>T	p.K164*	Hupki MEF	L157 HUF (P/P)	None	19030178	1956:22
1956	B(a)P-7,8-dione	g.7675122T>A	c.490A>T	p.K164*	Yeast reporter gene assay	BPQ-A5	None	12067251	1956:255
1956	B(a)P-7,8-dione	g.7675122T>A	c.490A>T	p.K164*	Yeast reporter gene assay	BPQ-A3	None	12067251	1956:256
4384	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673573T>A	c.955A>T	p.K319*	Yeast reporter gene assay	MNNG-30	None	12067251	4384:228
1527	aristolochic acid	g.7675197T>A	c.415A>T	p.K139*	Hupki MEF	L15 HUF (R/R)	None	19030178	1527:36
1527	anti-B(a)PDE	g.7675197T>A	c.415A>T	p.K139*	Yeast reporter gene assay	Am-8	methylated TP53 gene	22768918	1527:542
3068	dimethylbenz(a)anthracene-3,4-dione	g.7674255G>C	c.708C>G	p.Y236*	Yeast reporter gene assay	DB-56	None	22768918	3068:490
1046	anti-B(a)PDE	g.7676060G>C	c.309C>G	p.Y103*	Yeast reporter gene assay	P-3	None	22768918	1046:508
3029	dimethylbenz(a)anthracene-3,4-dione	g.7674261G>C	c.702C>G	p.Y234*	Yeast reporter gene assay	DB-14	None	22768918	3029:489
2394	anti-B(a)PDE	g.7674957G>A	c.574C>T	p.Q192*	Yeast reporter gene assay	Am-50	methylated TP53 gene	22768918	2394:558
1972	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675119G>A	c.493C>T	p.Q165*	Hupki MEF	MNNG 98 HUF (R/P)	None	19030178	1972:45
1972	benz(a)anthracene-3,4-dione	g.7675119G>A	c.493C>T	p.Q165*	Yeast reporter gene assay	BAQ-43	None	22768918	1972:415
1972	B(a)P-7,8-dione	g.7675119G>A	c.493C>T	p.Q165*	Yeast reporter gene assay	OGG1-16	OGG1 knock-out yeast	23117049	1972:649
1605	dimethylbenz(a)anthracene-3,4-dione	g.7675182G>A	c.430C>T	p.Q144*	Yeast reporter gene assay	DB-41	None	22768918	1605:463
4360	B(a)P-7,8-dione	g.7673579G>A	c.949C>T	p.Q317*	Yeast reporter gene assay	BPQ-A12	None	12067251	4360:297
4360	B(a)P-7,8-dione	g.7673579G>A	c.949C>T	p.Q317*	Yeast reporter gene assay	WT-25P	Wild-type yeast	23117049	4360:607
4360	B(a)P-7,8-dione	g.7673579G>A	c.949C>T	p.Q317*	Yeast reporter gene assay	WT-43Z	Wild-type yeast	23117049	4360:622
4360	B(a)P-7,8-dione	g.7673579G>A	c.949C>T	p.Q317*	Yeast reporter gene assay	APN1-34	APN1 knock-out yeast	23117049	4360:734
2003	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675113G>A	c.499C>T	p.Q167*	Yeast reporter gene assay	MNNG-2	None	12067251	2003:218
2003	B(a)P-7,8-dione	g.7675113G>A	c.499C>T	p.Q167*	Yeast reporter gene assay	BPQ-BPQ2	None	12067251	2003:257
2003	dimethylbenz(a)anthracene-3,4-dione	g.7675113G>A	c.499C>T	p.Q167*	Yeast reporter gene assay	DB-49	None	22768918	2003:472
1628	B(a)P-3,6 dione	g.7675175C>T	c.437G>A	p.W146*	Yeast reporter gene assay	3,6-67	None	22768918	1628:391
1628	B(a)P-3,6 dione	g.7675175C>T	c.437G>A	p.W146*	Yeast reporter gene assay	3,6-68	None	22768918	1628:393
4066	B(a)P-7,8-dione	g.7673740C>A	c.880G>T	p.E294*	Yeast reporter gene assay	OGG1-28	OGG1 knock-out yeast	23117049	4066:655
4121	dimethylbenz(a)anthracene-3,4-dione	g.7673728C>A	c.892G>T	p.E298*	Yeast reporter gene assay	DB-7	None	22768918	4121:504
4121	anti-B(a)PDE	g.7673728C>A	c.892G>T	p.E298*	Yeast reporter gene assay	F-25	None	22768918	4121:520
4121	B(a)P-7,8-dione	g.7673728C>A	c.892G>T	p.E298*	Yeast reporter gene assay	OGG1-44Z	OGG1 knock-out yeast	23117049	4121:674
4121	B(a)P-7,8-dione	g.7673728C>A	c.892G>T	p.E298*	Yeast reporter gene assay	APN1-39	APN1 knock-out yeast	23117049	4121:735
4121	acetaldehyde	g.7673728C>A	c.892G>T	p.E298*	Human fibroblasts AG1521 (FASAY)	Ac-37	Mutations identified on RNA by FASAY	18242117	4121:828
4121	acetaldehyde	g.7673728C>A	c.892G>T	p.E298*	Human fibroblasts AG1521 (FASAY)	Ac-38	Mutations identified on RNA by FASAY	18242117	4121:860
3934	B(a)P radical cations	g.7673767C>A	c.853G>T	p.E285*	Yeast reporter gene assay	RC-5	None	22768918	3934:308
3934	benz(a)anthracene-3,4-dione	g.7673767C>A	c.853G>T	p.E285*	Yeast reporter gene assay	BAQ-5	None	22768918	3934:454
4608	B(a)P-7,8-dione	g.7670694C>A	c.1015G>T	p.E339*	Yeast reporter gene assay	BPQ-B89	None	12067251	4608:298
4575	B(a)P-7,8-dione	g.7670703C>A	c.1006G>T	p.E336*	Yeast reporter gene assay	OGG1-55Z	OGG1 knock-out yeast	23117049	4575:681
2231	B(a)P-7,8-dione	g.7675074C>A	c.538G>T	p.E180*	Yeast reporter gene assay	WT-62Z	Wild-type yeast	23117049	2231:627
2231	B(a)P-7,8-dione	g.7675074C>A	c.538G>T	p.E180*	Yeast reporter gene assay	OGG1-1A	OGG1 knock-out yeast	23117049	2231:637
2568	dimethylbenz(a)anthracene-3,4-dione	g.7674921C>A	c.610G>T	p.E204*	Yeast reporter gene assay	DB-11	None	22768918	2568:483
656	B(a)P-1,6 dione	g.7676167C>A	c.202G>T	p.E68*	Yeast reporter gene assay	1,6-21	None	22768918	656:349
656	B(a)P-1,6 dione	g.7676167C>A	c.202G>T	p.E68*	Yeast reporter gene assay	1,6-22	None	22768918	656:350
3965	B(a)P-7,8-dione	g.7673761C>A	c.859G>T	p.E287*	Yeast reporter gene assay	OGG1-12	OGG1 knock-out yeast	23117049	3965:647
3965	B(a)P-7,8-dione	g.7673761C>A	c.859G>T	p.E287*	Yeast reporter gene assay	OGG1-13	OGG1 knock-out yeast	23117049	3965:648
3965	B(a)P-7,8-dione	g.7673761C>A	c.859G>T	p.E287*	Yeast reporter gene assay	OGG1-23	OGG1 knock-out yeast	23117049	3965:652
2870	B(a)P-7,8-dione	g.7674861C>A	c.670G>T	p.E224*	Yeast reporter gene assay	BPQ-B96	None	12067251	2870:273
2066	benz(a)anthracene-3,4-dione	g.7675101C>A	c.511G>T	p.E171*	Yeast reporter gene assay	BAQ-20	None	22768918	2066:421
2066	benz(a)anthracene-3,4-dione	g.7675101C>A	c.511G>T	p.E171*	Yeast reporter gene assay	BAQ-26	None	22768918	2066:422
2066	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675101C>A	c.511G>T	p.E171*	Hupki-XPAnull MEF	XN-BP-238	None	25847421	2066:893
2220	spontaneous immortalization	g.7675077G>A	c.535C>T	p.H179Y	Hupki MEF	HUF-CO-29	None	20118236	2220:147
2220	B(a)P-7,8-dione	g.7675077G>A	c.535C>T	p.H179Y	Yeast reporter gene assay	BPQ-A52	None	12067251	2220:262
2220	B(a)P (benzo(a)Pyrene)	g.7675077G>A	c.535C>T	p.H179Y	Human fibroblasts AG1521 (FASAY)	BaP-14	Mutations identified on RNA by FASAY	22319594	2220:761
2408	benz(a)anthracene-3,4-dione	g.7674954G>A	c.577C>T	p.H193Y	Yeast reporter gene assay	BAQ-60	None	22768918	2408:429
3800	B(a)P-7,8-dione	g.7673790C>T	c.830G>A	p.C277Y	Yeast reporter gene assay	WT-21P	Wild-type yeast	23117049	3800:603
3800	B(a)P-7,8-dione	g.7673790C>T	c.830G>A	p.C277Y	Yeast reporter gene assay	APN1-43	APN1 knock-out yeast	23117049	3800:738
3800	B(a)P-7,8-dione	g.7673790C>T	c.830G>A	p.C277Y	Yeast reporter gene assay	APN1-52	APN1 knock-out yeast	23117049	3800:742
3800	B(a)P (benzo(a)Pyrene)	g.7673790C>T	c.830G>A	p.C277Y	Human fibroblasts AG1521 (FASAY)	BaP-29	Mutations identified on RNA by FASAY	22319594	3800:771
3800	3-nitrobenzanthrone	g.7673790C>T	c.830G>A	p.C277Y	Hupki-XPAnull MEF	XN-3N-141	None	26723900	3800:937
2304	B(a)P-7,8-dione	g.7675056C>A	c.556G>T	p.D186Y	Yeast reporter gene assay	APN1-27	APN1 knock-out yeast	23117049	2304:729
1688	B(a)P-3,6 dione	g.7675165G>T	c.447C>A	p.S149S	Yeast reporter gene assay	3,6-72	None	22768918	1688:397
1688	benz(a)anthracene-3,4-dione	g.7675165G>T	c.447C>A	p.S149S	Yeast reporter gene assay	BAQ-67	None	22768918	1688:408
3524	benz(a)anthracene-3,4-dione	g.7674183G>T	c.780C>A	p.S260S	Yeast reporter gene assay	BAQ-42	None	22768918	3524:446
3025	anti-B(a)PDE	g.7674262T>G	c.701A>C	p.Y234S	Yeast reporter gene assay	Am-3	methylated TP53 gene	22768918	3025:564
3025	B(a)P-7,8-dione	g.7674262T>G	c.701A>C	p.Y234S	Yeast reporter gene assay	WT-3P	Wild-type yeast	23117049	3025:599
3405	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674206T>A	c.757A>T	p.T253S	Hupki-XPAnull MEF	XN-BP-229	None	25847421	3405:900
4296	B(a)P-1,6 dione	g.7673594T>A	c.934A>T	p.T312S	Yeast reporter gene assay	1,6-61	None	22768918	4296:357
1755	B(a)P-7,8-dione	g.7675155G>A	c.457C>T	p.P153S	Yeast reporter gene assay	WT-17	Wild-type yeast	23117049	1755:592
1718	B(a)P-7,8-dione	g.7675161G>A	c.451C>T	p.P151S	Yeast reporter gene assay	BPQ-I20	None	12067251	1718:246
1718	B(a)P-3,6 dione	g.7675161G>A	c.451C>T	p.P151S	Yeast reporter gene assay	3,6-16	None	22768918	1718:379
1718	AFB1 (aflatoxin)	g.7675161G>A	c.451C>T	p.P151S	Human fibroblasts AG1521 (FASAY)	AFB1-12	Mutations identified on RNA by FASAY	18725321	1718:787
4265	acetaldehyde	g.7673603G>A	c.925C>T	p.P309S	Human fibroblasts AG1521 (FASAY)	Ac-41	Mutations identified on RNA by FASAY	18242117	4265:831
3343	B(a)P-7,8-dione	g.7674215G>A	c.748C>T	p.P250S	Yeast reporter gene assay	APN1-42	APN1 knock-out yeast	23117049	3343:737
3343	B(a)P-7,8-dione	g.7674215G>A	c.748C>T	p.P250S	Yeast reporter gene assay	APN1-49	APN1 knock-out yeast	23117049	3343:740
2806	B(a)P-7,8-dione	g.7674876G>A	c.655C>T	p.P219S	Yeast reporter gene assay	WT-9B	Wild-type yeast	23117049	2806:589
2167	anti-B(a)PDE	g.7675085C>G	c.527G>C	p.C176S	Yeast reporter gene assay	F10	None	18489080	2167:198
3186	B(a)P radical cations	g.7674238C>G	c.725G>C	p.C242S	Yeast reporter gene assay	RC-2	None	22768918	3186:305
1906	B(a)P-1,6 dione	g.7675131C>A	c.481G>T	p.A161S	Yeast reporter gene assay	1,6-82	None	22768918	1906:362
3787	B(a)P-7,8-dione	g.7673794C>A	c.826G>T	p.A276S	Yeast reporter gene assay	WT-38Z	Wild-type yeast	23117049	3787:618
2346	benz(a)anthracene-3,4-dione	g.7674966C>A	c.565G>T	p.A189S	Yeast reporter gene assay	BAQ-21	None	22768918	2346:427
1877	anti-B(a)PDE	g.7675137C>A	c.475G>T	p.A159S	Yeast reporter gene assay	Am-4	methylated TP53 gene	22768918	1877:546
2844	B(a)P-7,8-dione	g.7674867G>A	c.664C>T	p.P222S	Yeast reporter gene assay	OGG1-48Z	OGG1 knock-out yeast	23117049	2844:677
1736	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675158G>A	c.454C>T	p.P152S	Hupki MEF	MNNG 88 HUF (R/P)	None	19030178	1736:42
2820	dimethylbenz(a)anthracene-3,4-dione	g.7674872T>G	c.659A>C	p.Y220S	Yeast reporter gene assay	DB-50	None	22768918	2820:486
2584	spontaneous immortalization	g.7674917T>G	c.614A>C	p.Y205S	Hupki MEF	HUF-CO-A-15	None	18765419	2584:118
525	aristolochic acid	g.7676206T>A	c.163A>T	p.T55S	Hupki MEF	L152 HUF (P/P)	None	19030178	525:17
1574	dimethylbenz(a)anthracene-3,4-dione	g.7675188G>A	c.424C>T	p.P142S	Yeast reporter gene assay	DB-1	None	22768918	1574:460
3812	UV radiation	g.7673788G>A	c.832C>T	p.P278S	Hupki skin	UV-7	None	11719445	3812:57
3812	B(a)P (benzo(a)Pyrene)	g.7673788G>A	c.832C>T	p.P278S	Hupki MEF	HUF-BaP-116	None	15805253	3812:71
3812	B(a)P radical cations	g.7673788G>A	c.832C>T	p.P278S	Yeast reporter gene assay	RC-15	None	22768918	3812:318
3812	B(a)P radical cations	g.7673788G>A	c.832C>T	p.P278S	Yeast reporter gene assay	RC-22	None	22768918	3812:325
2360	dimethylbenz(a)anthracene-3,4-dione	g.7674963G>A	c.568C>T	p.P190S	Yeast reporter gene assay	DB-52	None	22768918	2360:459
625	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7676176T>A	c.193A>T	p.R65*	Hupki-XPAnull MEF	XN-BP-292	None	25847421	625:883
2644	aristolochic acid	g.7674906T>A	c.625A>T	p.R209*	Hupki MEF	L128 HUF (P/P)	None	19030178	2644:14
2644	aristolochic acid	g.7674906T>A	c.625A>T	p.R209*	Hupki MEF	L156 HUF (P/P)	None	19030178	2644:21
2644	aristolochic acid	g.7674906T>A	c.625A>T	p.R209*	Hupki MEF	L6 HUF (R/R)	None	19030178	2644:26
2259	anti-B(a)PDE	g.7675066G>T	c.546C>A	p.C182*	Yeast reporter gene assay	anti-BPDE-5	None	12067251	2259:230
2259	benz(a)anthracene-3,4-dione	g.7675066G>T	c.546C>A	p.C182*	Yeast reporter gene assay	BAQ-29	None	22768918	2259:425
2259	dimethylbenz(a)anthracene-3,4-dione	g.7675066G>T	c.546C>A	p.C182*	Yeast reporter gene assay	DB-60	None	22768918	2259:479
2259	B(a)P-7,8-dione	g.7675066G>T	c.546C>A	p.C182*	Yeast reporter gene assay	WT-30Z	Wild-type yeast	23117049	2259:614
3189	B(a)P-7,8-dione	g.7674237G>T	c.726C>A	p.C242*	Yeast reporter gene assay	OGG1-10	OGG1 knock-out yeast	23117049	3189:646
3189	B(a)P-7,8-dione	g.7674237G>T	c.726C>A	p.C242*	Yeast reporter gene assay	OGG1-19	OGG1 knock-out yeast	23117049	3189:650
3189	B(a)P-7,8-dione	g.7674237G>T	c.726C>A	p.C242*	Yeast reporter gene assay	OGG1-20	OGG1 knock-out yeast	23117049	3189:651
3189	B(a)P-7,8-dione	g.7674237G>T	c.726C>A	p.C242*	Yeast reporter gene assay	OGG1-27	OGG1 knock-out yeast	23117049	3189:654
2172	B(a)P-7,8-dione	g.7675084G>T	c.528C>A	p.C176*	Yeast reporter gene assay	BPQ-BQ2	None	12067251	2172:260
2172	B(a)P-3,6 dione	g.7675084G>T	c.528C>A	p.C176*	Yeast reporter gene assay	3,6-51	None	22768918	2172:389
2172	B(a)P-3,6 dione	g.7675084G>T	c.528C>A	p.C176*	Yeast reporter gene assay	3,6-55	None	22768918	2172:390
1566	B(a)P-3,6 dione	g.7675189G>T	c.423C>A	p.C141*	Yeast reporter gene assay	3,6-40	None	22768918	1566:386
1466	B(a)P-7,8-dione	g.7675207G>T	c.405C>A	p.C135*	Yeast reporter gene assay	BPQ-A57	None	12067251	1466:238
1466	anti-B(a)PDE	g.7675207G>T	c.405C>A	p.C135*	Yeast reporter gene assay	P-6	None	22768918	1466:510
2267	benz(a)anthracene-3,4-dione	g.7675064G>C	c.548C>G	p.S183*	Yeast reporter gene assay	BAQ-68	None	22768918	2267:426
2705	benz(a)anthracene-3,4-dione	g.7674894G>A	c.637C>T	p.R213*	Yeast reporter gene assay	BAQ54	None	18489080	2705:182
2705	anti-B(a)PDE	g.7674894G>A	c.637C>T	p.R213*	Yeast reporter gene assay	AM23	None	18489080	2705:206
2705	anti-B(a)PDE	g.7674894G>A	c.637C>T	p.R213*	Yeast reporter gene assay	Am-40	methylated TP53 gene	22768918	2705:560
2705	anti-B(a)PDE	g.7674894G>A	c.637C>T	p.R213*	Yeast reporter gene assay	Am-49	methylated TP53 gene	22768918	2705:561
2705	benzene	g.7674894G>A	c.637C>T	p.R213*	A549 human lung cell line	BIL15-BZ9	Mutations identified on RNA by FASAY	19862502	2705:947
2458	benz(a)anthracene-3,4-dione	g.7674945G>A	c.586C>T	p.R196*	Yeast reporter gene assay	BAQ-13	None	22768918	2458:434
2458	dimethylbenz(a)anthracene-3,4-dione	g.7674945G>A	c.586C>T	p.R196*	Yeast reporter gene assay	DB-5	None	22768918	2458:480
4226	B(a)P-7,8-dione	g.7673704G>A	c.916C>T	p.R306*	Yeast reporter gene assay	BPQ-A15	None	12067251	4226:272
4226	B(a)P-7,8-dione	g.7673704G>A	c.916C>T	p.R306*	Yeast reporter gene assay	BPQ-A44	None	12067251	4226:295
922	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7676096C>T	c.273G>A	p.W91*	Hupki MEF	XW-BP-91	None	25847421	922:861
1634	B(a)P-7,8-dione	g.7675174C>T	c.438G>A	p.W146*	Yeast reporter gene assay	WT-19P	Wild-type yeast	23117049	1634:601
2498	B(a)P-7,8-dione	g.7674936C>A	c.595G>T	p.G199*	Yeast reporter gene assay	BPQ-BPQ5	None	12067251	2498:269
3617	dimethylbenz(a)anthracene-3,4-dione	g.7673824C>A	c.796G>T	p.G266*	Yeast reporter gene assay	DB-43	None	22768918	3617:499
4453	benz(a)anthracene-3,4-dione	g.7673555C>A	c.973G>T	p.G325*	Yeast reporter gene assay	BAQ-14	None	22768918	4453:455
4453	anti-B(a)PDE	g.7673555C>A	c.973G>T	p.G325*	Yeast reporter gene assay	Am-2	methylated TP53 gene	22768918	4453:573
4453	B(a)P-7,8-dione	g.7673555C>A	c.973G>T	p.G325*	Yeast reporter gene assay	WT-27Z	Wild-type yeast	23117049	4453:612
1943	3-nitrobenzanthrone	g.7675124T>C	c.488A>G	p.Y163C	Hupki MEF	HUF-3NBA-J-135	None	18765419	1943:80
1943	3-nitrobenzanthrone	g.7675124T>C	c.488A>G	p.Y163C	Hupki MEF	HUF-3NBA-J-136	None	18765419	1943:81
1943	3-nitrobenzanthrone	g.7675124T>C	c.488A>G	p.Y163C	Hupki MEF	HUF-3NBA-J-145	None	18765419	1943:82
1943	3-nitrobenzanthrone	g.7675124T>C	c.488A>G	p.Y163C	Hupki MEF	HUF-3NBA-J-148	None	18765419	1943:83
1943	N-hydroxy-3-aminobenzanthrone	g.7675124T>C	c.488A>G	p.Y163C	Hupki MEF	HUF-NOH3A-A-60	None	18765419	1943:109
3064	3-nitrobenzanthrone	g.7674256T>C	c.707A>G	p.Y236C	Hupki MEF	HUF-3NBA-J-120	None	18765419	3064:90
3064	3-nitrobenzanthrone	g.7674256T>C	c.707A>G	p.Y236C	Hupki MEF	HUF-3NBA-J-256	None	18765419	3064:91
3064	3-nitrobenzanthrone	g.7674256T>C	c.707A>G	p.Y236C	Hupki MEF	XW-3N-7	None	26723900	3064:925
4309	aristolochic acid	g.7673591T>A	c.937A>T	p.S313C	Hupki MEF	L14 HUF (R/R)	None	19030178	4309:35
1340	B(a)P (benzo(a)Pyrene)	g.7675232G>C	c.380C>G	p.S127C	Human fibroblasts AG1521 (FASAY)	BaP-6	Mutations identified on RNA by FASAY	22319594	1340:753
1858	B(a)P-7,8-dione	g.7675140G>A	c.472C>T	p.R158C	Yeast reporter gene assay	WT-74Z	Wild-type yeast	23117049	1858:635
1811	B(a)P-7,8-dione	g.7675146G>A	c.466C>T	p.R156C	Yeast reporter gene assay	WT-26Z	Wild-type yeast	23117049	1811:611
2242	B(a)P-7,8-dione	g.7675071G>A	c.541C>T	p.R181C	Yeast reporter gene assay	OGG1-1B	OGG1 knock-out yeast	23117049	2242:638
3901	B(a)P-7,8-dione	g.7673773G>A	c.847C>T	p.R283C	Yeast reporter gene assay	WT-65Z	Wild-type yeast	23117049	3901:630
3238	B(a)P-7,8-dione	g.7674230C>A	c.733G>T	p.G245C	Yeast reporter gene assay	BPQ-I27	None	12067251	3238:281
3238	B(a)P-7,8-dione	g.7674230C>A	c.733G>T	p.G245C	Yeast reporter gene assay	OGG1-60Z	OGG1 knock-out yeast	23117049	3238:685
3238	AFB1 (aflatoxin)	g.7674230C>A	c.733G>T	p.G245C	Human fibroblasts AG1521 (FASAY)	AFB1-30	Mutations identified on RNA by FASAY	18725321	3238:799
3218	dimethylbenz(a)anthracene-3,4-dione	g.7674233C>A	c.730G>T	p.G244C	Yeast reporter gene assay	DB13	None	18489080	3218:192
1770	B(a)P-7,8-dione	g.7675152C>A	c.460G>T	p.G154C	Yeast reporter gene assay	BPQ-BQ11	None	12067251	1770:249
1770	B(a)P radical cations	g.7675152C>A	c.460G>T	p.G154C	Yeast reporter gene assay	RC-29	None	22768918	1770:332
1770	B(a)P radical cations	g.7675152C>A	c.460G>T	p.G154C	Yeast reporter gene assay	RC-32	None	22768918	1770:335
1770	B(a)P-7,8-dione	g.7675152C>A	c.460G>T	p.G154C	Yeast reporter gene assay	OGG1-38ZA	OGG1 knock-out yeast	23117049	1770:669
1770	B(a)P-7,8-dione	g.7675152C>A	c.460G>T	p.G154C	Yeast reporter gene assay	OGG1-69Z	OGG1 knock-out yeast	23117049	1770:694
2899	dimethylbenz(a)anthracene-3,4-dione	g.7674287C>A	c.676G>T	p.G226C	Yeast reporter gene assay	DB-25	None	22768918	2899:469
3314	aristolochic acid	g.7674218T>A	c.745A>T	p.R249W	Hupki MEF	L129 HUF (P/P)	None	19030178	3314:15
3314	aristolochic acid	g.7674218T>A	c.745A>T	p.R249W	Hupki MEF	L155 HUF (P/P)	None	19030178	3314:20
2173	aristolochic acid	g.7675084G>C	c.528C>G	p.C176W	Hupki MEF	L7 HUF (R/R)	None	19030178	2173:27
2173	3-nitrobenzanthrone	g.7675084G>C	c.528C>G	p.C176W	Hupki MEF	HUF-3NBA-J-254	None	18765419	2173:85
2173	spontaneous immortalization	g.7675084G>C	c.528C>G	p.C176W	Hupki MEF	HUF-CO-25	None	20118236	2173:143
2173	spontaneous immortalization	g.7675084G>C	c.528C>G	p.C176W	Hupki MEF	HUF-CO-26	None	20118236	2173:144
1467	aristolochic acid	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	L104 HUF (R/P)	None	19030178	1467:7
1467	aristolochic acid	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	L130 HUF (P/P)	None	19030178	1467:16
1467	aristolochic acid	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	L153 HUF (P/P)	None	19030178	1467:18
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-II5	None	15805253	1467:75
1467	N-hydroxy-3-aminobenzanthrone	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-NOH3A-A-41	None	18765419	1467:108
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-J-224	None	18765419	1467:114
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-8	None	20118236	1467:126
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-9	None	20118236	1467:127
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-10	None	20118236	1467:128
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-11	None	20118236	1467:129
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-12	None	20118236	1467:130
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-13	None	20118236	1467:131
1467	spontaneous immortalization	g.7675207G>C	c.405C>G	p.C135W	Hupki MEF	HUF-CO-14	None	20118236	1467:132
1467	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675207G>C	c.405C>G	p.C135W	Hupki-XPAnull MEF	XN-BP-300	None	25847421	1467:887
3879	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673776G>A	c.844C>T	p.R282W	Hupki MEF	MNNG 80 HUF (R/P)	None	19030178	3879:40
3879	3-nitrobenzanthrone	g.7673776G>A	c.844C>T	p.R282W	Hupki MEF	XW-3N-37	None	26723900	3879:928
3294	UV radiation	g.7674221G>A	c.742C>T	p.R248W	Hupki skin	UV-4	None	11719445	3294:54
3294	anti-B(a)PDE	g.7674221G>A	c.742C>T	p.R248W	Yeast reporter gene assay	Am-1	methylated TP53 gene	22768918	3294:566
3294	3-nitrobenzanthrone	g.7674221G>A	c.742C>T	p.R248W	Hupki MEF	XW-3N-43	None	26723900	3294:926
3633	dimethylbenz(a)anthracene-3,4-dione	g.7673821G>A	c.799C>T	p.R267W	Yeast reporter gene assay	DB31	None	18489080	3633:211
3633	B(a)P-7,8-dione	g.7673821G>A	c.799C>T	p.R267W	Yeast reporter gene assay	WT-75Z	Wild-type yeast	23117049	3633:636
3633	acetaldehyde	g.7673821G>A	c.799C>T	p.R267W	Human fibroblasts AG1521 (FASAY)	Ac-25	Mutations identified on RNA by FASAY	18242117	3633:822
3633	acetaldehyde	g.7673821G>A	c.799C>T	p.R267W	Human fibroblasts AG1521 (FASAY)	Ac-26	Mutations identified on RNA by FASAY	18242117	3633:854
1211	B(a)P (benzo(a)Pyrene)	g.7676020C>A	c.349G>T	p.G117W	Hupki MEF	HUF-BaP-14	None	15805253	1211:65
3832	B(a)P (benzo(a)Pyrene)	g.7673785C>A	c.835G>T	p.G279W	Hupki MEF	HUF-BaP-116	None	15805253	3832:72
3832	dimethylbenz(a)anthracene-3,4-dione	g.7673785C>A	c.835G>T	p.G279W	Yeast reporter gene assay	DB48	None	18489080	3832:195
3832	B(a)P-7,8-dione	g.7673785C>A	c.835G>T	p.G279W	Yeast reporter gene assay	OGG1-45Z	OGG1 knock-out yeast	23117049	3832:675
5079	B(a)P-7,8-dione	g.7669626C>A	c.1165G>T	p.G389W	Yeast reporter gene assay	APN1-50	APN1 knock-out yeast	23117049	5079:741
4051	B(a)P-7,8-dione	g.7673743C>A	c.877G>T	p.G293W	Yeast reporter gene assay	OGG1-74ZB	OGG1 knock-out yeast	23117049	4051:698
2821	B(a)P-1,6 dione	g.7674872T>C	c.659A>G	p.Y220C	Yeast reporter gene assay	1,6-37	None	22768918	2821:354
2585	B(a)P-7,8-dione	g.7674917T>C	c.614A>G	p.Y205C	Yeast reporter gene assay	WT-14	Wild-type yeast	23117049	2585:591
1130	anti-B(a)PDE	g.7676041G>A	c.328C>T	p.R110C	Yeast reporter gene assay	P-6	None	22768918	1130:509
3730	aristolochic acid	g.7673803G>A	c.817C>T	p.R273C	Hupki MEF	L98 HUF (R/P)	None	19030178	3730:5
3730	spontaneous immortalization	g.7673803G>A	c.817C>T	p.R273C	Hupki MEF	HUF-CO-15	None	15805253	3730:73
3730	spontaneous immortalization	g.7673803G>A	c.817C>T	p.R273C	Hupki MEF	HUF-CO-51	None	20118236	3730:169
3730	spontaneous immortalization	g.7673803G>A	c.817C>T	p.R273C	Hupki MEF	HUF-CO-52	None	20118236	3730:170
3730	acetaldehyde	g.7673803G>A	c.817C>T	p.R273C	Human fibroblasts AG1521 (FASAY)	Ac-27	Mutations identified on RNA by FASAY	18242117	3730:823
3730	acetaldehyde	g.7673803G>A	c.817C>T	p.R273C	Human fibroblasts AG1521 (FASAY)	Ac-28	Mutations identified on RNA by FASAY	18242117	3730:855
3191	dimethylbenz(a)anthracene-3,4-dione	g.7674237G>A	c.726C>T	p.C242C	Yeast reporter gene assay	DB-57	None	22768918	3191:493
1568	AFB1 (aflatoxin)	g.7675189G>A	c.423C>T	p.C141C	Human fibroblasts AG1521 (FASAY)	AFB1-9	Mutations identified on RNA by FASAY	18725321	1568:784
3587	B(a)P-1,6 dione	g.7673830G>A	c.790C>T	p.L264L	Yeast reporter gene assay	1,6-4	None	22768918	3587:340
2268	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7675064G>A	c.548C>T	p.S183L	Yeast reporter gene assay	MNNG-17	None	12067251	2268:225
1924	B(a)P-7,8-dione	g.7675128T>A	c.484A>T	p.I162F	Yeast reporter gene assay	OGG1-38ZB	OGG1 knock-out yeast	23117049	1924:670
1326	B(a)P (benzo(a)Pyrene)	g.7675235T>A	c.377A>T	p.Y126F	Human fibroblasts AG1521 (FASAY)	BaP-3	Mutations identified on RNA by FASAY	22319594	1326:751
3369	B(a)P-7,8-dione	g.7674212T>A	c.751A>T	p.I251F	Yeast reporter gene assay	OGG1-	OGG1 knock-out yeast	23117049	3369:692
2442	3-nitrobenzanthrone	g.7674948T>A	c.583A>T	p.I195F	Hupki MEF	HUF-3NBA-J-254	None	18765419	2442:86
1341	anti-B(a)PDE	g.7675232G>A	c.380C>T	p.S127F	Yeast reporter gene assay	F-18	None	22768918	1341:513
1341	B(a)P (benzo(a)Pyrene)	g.7675232G>A	c.380C>T	p.S127F	Human fibroblasts AG1521 (FASAY)	BaP-4	Mutations identified on RNA by FASAY	22319594	1341:752
1002	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7676073G>A	c.296C>T	p.S99F	Hupki MEF	MNNG 96 HUF (R/P)	None	19030178	1002:44
3170	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674241G>A	c.722C>T	p.S241F	Hupki MEF	MNNG 77 HUF (R/P)	None	19030178	3170:38
3170	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674241G>A	c.722C>T	p.S241F	Hupki MEF	MNNG 105 HUF (R/P)	None	19030178	3170:47
3170	B(a)P-7,8-dione	g.7674241G>A	c.722C>T	p.S241F	Yeast reporter gene assay	BPQ-I22	None	12067251	3170:275
4324	B(a)P-7,8-dione	g.7673587G>A	c.941C>T	p.S314F	Yeast reporter gene assay	BPQ-A55	None	12067251	4324:296
4324	anti-B(a)PDE	g.7673587G>A	c.941C>T	p.S314F	Yeast reporter gene assay	Am-49	methylated TP53 gene	22768918	4324:562
4324	B(a)P-7,8-dione	g.7673587G>A	c.941C>T	p.S314F	Yeast reporter gene assay	WT-67ZB	Wild-type yeast	23117049	4324:632
2168	spontaneous immortalization	g.7675085C>A	c.527G>T	p.C176F	Hupki MEF	HUF-CO-27	None	20118236	2168:145
2168	B(a)P-7,8-dione	g.7675085C>A	c.527G>T	p.C176F	Yeast reporter gene assay	APN1-12	APN1 knock-out yeast	23117049	2168:713
2168	B(a)P-7,8-dione	g.7675085C>A	c.527G>T	p.C176F	Yeast reporter gene assay	APN1-19	APN1 knock-out yeast	23117049	2168:720
1837	B(a)P (benzo(a)Pyrene)	g.7675143C>A	c.469G>T	p.V157F	Hupki MEF	HUF-BaP-D14B	None	15805253	1837:66
1837	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7675143C>A	c.469G>T	p.V157F	Hupki-XPAnull MEF	XN-BP-268	None	25847421	1837:890
1837	3-nitrobenzanthrone	g.7675143C>A	c.469G>T	p.V157F	Hupki-XPAnull MEF	XN-3N-117	None	26723900	1837:929
1837	3-nitrobenzanthrone	g.7675143C>A	c.469G>T	p.V157F	Hupki-XPAnull MEF	XN-3N-120	None	26723900	1837:930
1463	B(a)P-7,8-dione	g.7675208C>A	c.404G>T	p.C135F	Yeast reporter gene assay	BPQ-B90	None	12067251	1463:239
1463	dimethylbenz(a)anthracene-3,4-dione	g.7675208C>A	c.404G>T	p.C135F	Yeast reporter gene assay	DB-46	None	22768918	1463:456
1463	B(a)P-7,8-dione	g.7675208C>A	c.404G>T	p.C135F	Yeast reporter gene assay	OGG1-3	OGG1 knock-out yeast	23117049	1463:641
1463	B(a)P-7,8-dione	g.7675208C>A	c.404G>T	p.C135F	Yeast reporter gene assay	OGG1-64Z	OGG1 knock-out yeast	23117049	1463:688
3187	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7674238C>A	c.725G>T	p.C242F	Yeast reporter gene assay	MNNG-5	None	12067251	3187:220
3187	B(a)P-7,8-dione	g.7674238C>A	c.725G>T	p.C242F	Yeast reporter gene assay	BPQ-A23	None	12067251	3187:276
3187	dimethylbenz(a)anthracene-3,4-dione	g.7674238C>A	c.725G>T	p.C242F	Yeast reporter gene assay	DB-40	None	22768918	3187:492
2033	aristolochic acid	g.7675107T>A	c.505A>T	p.M169L	Hupki MEF	L113 HUF (R/P)	None	19030178	2033:11
3602	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673827G>A	c.793C>T	p.L265L	Yeast reporter gene assay	MNNG-1	None	12067251	3602:217
2333	anti-B(a)PDE	g.7674969G>A	c.562C>T	p.L188L	Yeast reporter gene assay	Am-55	methylated TP53 gene	22768918	2333:556
1630	B(a)P-7,8-dione	g.7675175C>A	c.437G>T	p.W146L	Yeast reporter gene assay	BPQ-BQ11	None	12067251	1630:250
2096	3-nitrobenzanthrone	g.7675095C>A	c.517G>T	p.V173L	Hupki MEF	HUF-3NBA-J-134	None	18765419	2096:84
2551	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7674924C>A	c.607G>T	p.V203L	Hupki MEF	XW-BP-2	None	25847421	2551:869
2425	aristolochic acid	g.7674951G>A	c.580C>T	p.L194F	Hupki MEF	L154 HUF (P/P)	None	19030178	2425:19
2425	spontaneous immortalization	g.7674951G>A	c.580C>T	p.L194F	Hupki MEF	HUF-CO-17	None	15805253	2425:74
2425	spontaneous immortalization	g.7674951G>A	c.580C>T	p.L194F	Hupki MEF	HUF-CO-30	None	20118236	2425:148
4336	B(a)P-1,6 dione	g.7673584G>A	c.944C>T	p.S315F	Yeast reporter gene assay	1,6-8	None	22768918	4336:342
4336	benz(a)anthracene-3,4-dione	g.7673584G>A	c.944C>T	p.S315F	Yeast reporter gene assay	BAQ-60	None	22768918	4336:432
3752	3-nitrobenzanthrone	g.7673800C>A	c.820G>T	p.V274F	Hupki MEF	HUF-3NBA-J-120	None	18765419	3752:101
3752	3-nitrobenzanthrone	g.7673800C>A	c.820G>T	p.V274F	Hupki MEF	HUF-3NBA-J-256	None	18765419	3752:102
3752	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673800C>A	c.820G>T	p.V274F	Hupki-XPAnull MEF	XN-BP-254	None	25847421	3752:908
3773	spontaneous immortalization	g.7673796C>A	c.824G>T	p.C275F	Hupki MEF	HUF-CO-53	None	20118236	3773:171
3773	B(a)PDE (benzo(a)Pyrene diol epoxide)	g.7673796C>A	c.824G>T	p.C275F	Hupki MEF	XW-BP-9	None	25847421	3773:880
3802	B(a)P (benzo(a)Pyrene)	g.7673790C>A	c.830G>T	p.C277F	Human fibroblasts AG1521 (FASAY)	BaP-30	Mutations identified on RNA by FASAY	22319594	3802:772
3802	3-nitrobenzanthrone	g.7673790C>A	c.830G>T	p.C277F	Hupki-XPAnull MEF	XN-3N-140	None	26723900	3802:936
3813	UV radiation	g.7673787_7673788delinsAA	c.832_833delinsTT	p.P278F	Hupki skin	UV-9	None	11719445	3813:59
3813	MNNG (N-methyl-N-nitro-N-nitrosoguanidine)	g.7673787_7673788delinsAA	c.832_833delinsTT	p.P278F	Yeast reporter gene assay	MNNG-26	None	12067251	3813:226
3289	UV radiation	g.7674221_7674222delinsAA	c.741_742delinsTT	p.R248W	Hupki skin	UV-6	None	11719445	3289:56
6795	anti-B(a)PDE	g.7674233_7674234delinsGT	c.729_730delinsAC	p.M243_G244delinsIR	Yeast reporter gene assay	Am-11	methylated TP53 gene	22768918	6795:574
6794	anti-B(a)PDE	g.7675077_7675081delinsAATAA	c.531_535delinsTTATT	p.[H178Y;H179Y]	Yeast reporter gene assay	Am-34	methylated TP53 gene	22768918	6794:552