View Data: Systematic Functional Assessment of p53 Mutant Proteins in Yeast Assays
| ProtDescription | AAchange | Codon_Number | WAF1nWT | MDM2nWT | BAXnWT | h1433snWT | AIP1nWT | GADD45nWT | NOXAnWT | P53R2nWT | WAF1nWT_Saos2 | MDM2nWT_Saos2 | BAXnWT_Saos2 | h1433snWT_Saos2 | AIP1nWT_Saos2 | PUMAnWT_Saos2 | SubG1nWT_Saos2 | Oligomerisation_yeast | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ProtDescription | AAchange | Codon_Number | WAF1nWT | MDM2nWT | BAXnWT | h1433snWT | AIP1nWT | GADD45nWT | NOXAnWT | P53R2nWT | WAF1nWT_Saos2 | MDM2nWT_Saos2 | BAXnWT_Saos2 | h1433snWT_Saos2 | AIP1nWT_Saos2 | PUMAnWT_Saos2 | SubG1nWT_Saos2 | Oligomerisation_yeast | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| p.A119D | A119D | 119 | 24.5 | 15.4 | 13.5 | 7.9 | 4.6 | 53.2 | 9.7 | 91.6 | 33.3 | 74.1 | 2.6 | 18.8 | -1.8 | 154.9 | 142.2 | ||
| p.A119G | A119G | 119 | 53.5 | 24.0 | 14.1 | 50.8 | 27.5 | 91.6 | 122.7 | 109.9 | |||||||||
| p.A119P | A119P | 119 | 29.8 | 17.3 | 12.4 | 43.7 | 21.9 | 81.0 | 107.2 | 116.6 | 62.6 | 104.2 | 80.2 | 108.1 | 38.1 | 139.3 | 106.6 | ||
| p.A119S | A119S | 119 | 101.2 | 56.6 | 43.1 | 92.9 | 48.6 | 91.9 | 138.9 | 106.7 | |||||||||
| p.A119T | A119T | 119 | 108.2 | 100.4 | 102.8 | 87.0 | 52.8 | 86.1 | 115.8 | 94.3 | |||||||||
| p.A119V | A119V | 119 | 29.1 | 30.2 | 18.7 | 51.1 | 31.3 | 65.8 | 84.4 | 89.4 | |||||||||
| p.A129D | A129D | 129 | 85.7 | 98.0 | 104.4 | 86.0 | 63.6 | 101.4 | 148.4 | 69.5 | |||||||||
| p.A129G | A129G | 129 | 79.4 | 78.1 | 84.8 | 84.7 | 65.8 | 94.8 | 110.5 | 77.4 | |||||||||
| p.A129P | A129P | 129 | 87.1 | 69.8 | 90.5 | 70.5 | 63.8 | 102.4 | 132.2 | 69.4 | |||||||||
| p.A129S | A129S | 129 | 103.0 | 94.2 | 102.4 | 84.1 | 58.5 | 104.5 | 125.0 | 86.1 |